Heated Humidified High-Flow Nasal Cannula in Children: State of the Art

被引:5
作者
Venanzi, Annamaria [1 ]
Di Filippo, Paola [1 ]
Santagata, Chiara [1 ]
Di Pillo, Sabrina [1 ]
Chiarelli, Francesco [1 ]
Attanasi, Marina [1 ]
机构
[1] Univ G dAnnunzio, Dept Pediat, I-66100 Chieti, Italy
关键词
heated humidified high-flow; children; respiratory failure; oxygen therapy; bronchiolitis; POSITIVE AIRWAY PRESSURE; ACUTE RESPIRATORY-FAILURE; OBSTRUCTIVE SLEEP-APNEA; OXYGEN-THERAPY; DEAD-SPACE; VIRAL BRONCHIOLITIS; PEDIATRIC-PATIENTS; VENTILATION; INFANTS; MANAGEMENT;
D O I
10.3390/biomedicines10102353
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
High-flow nasal cannula (HFNC) therapy is a non-invasive ventilatory support that has gained interest over the last ten years as a valid alternative to nasal continuous positive airway pressure (nCPAP) in children with respiratory failure. Its safety, availability, tolerability, and easy management have resulted its increasing usage, even outside intensive care units. Despite its wide use in daily clinical practice, there is still a lack of guidelines to standardize the use of HFNC. The aim of this review is to summarize current knowledge about the mechanisms of action, safety, clinical effects, and tolerance of HFNC in children, and to propose a clinical practices algorithm for children with respiratory failure.
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页数:14
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