BACKWARD BIFURCATION AND GLOBAL STABILITY IN AN EPIDEMIC MODEL WITH TREATMENT AND VACCINATION

被引:11
作者
Feng, Xiaomei [1 ,2 ]
Teng, Zhidong [1 ]
Wang, Kai [3 ]
Zhang, Fengqin [2 ]
机构
[1] Xinjiang Univ, Coll Math & Syst Sci, Urumqi 830046, Peoples R China
[2] Yuncheng Univ, Dept Math, Yuncheng 044000, Peoples R China
[3] Xinjiang Med Univ, Dept Med Engn & Technol, Urumqi 830011, Peoples R China
来源
DISCRETE AND CONTINUOUS DYNAMICAL SYSTEMS-SERIES B | 2014年 / 19卷 / 04期
基金
中国国家自然科学基金;
关键词
SVEIR epidemic model; global stability; backward bifurcation; compound matrices; SIS; DISEASE; EQUILIBRIA; DYNAMICS;
D O I
10.3934/dcdsb.2014.19.999
中图分类号
O29 [应用数学];
学科分类号
070104 ;
摘要
In this paper, we consider a class of epidemic models described by five nonlinear ordinary differential equations. The population is divided into susceptible, vaccinated, exposed, infectious, and recovered subclasses. One main feature of this kind of models is that treatment and vaccination are introduced to control and prevent infectious diseases. The existence and local stability of the endemic equilibria are studied. The occurrence of backward bifurcation is established by using center manifold theory. Moveover, global dynamics are studied by applying the geometric approach. We would like to mention that in the case of bistability, global results are difficult to obtain since there is no compact absorbing set. It is the first time that higher (greater than or equal to four) dimensional systems are discussed. We give sufficient conditions in terms of the system parameters by extending the method in Arino et al. [2]. Numerical simulations are also provided to support our theoretical results. By carrying out sensitivity analysis of the basic reproduction number in terms of some parameters, some effective measures to control infectious diseases are analyzed.
引用
收藏
页码:999 / 1025
页数:27
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