Familial and Hereditary Renal Cancer Syndromes

被引：27

作者：

Coleman, Jonathan A. ^{[1
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, Weill Cornell Med Coll, Dept Surg, Div Urol, New York, NY 10021 USA

来源：

UROLOGIC CLINICS OF NORTH AMERICA | 2008年 / 35卷 / 04期

关键词：

Hereditary kidney cancer; von Hippel-Lindau; Birt Hogg Dube; Hereditary leiomyomatosis renal cell carcinoma; Hereditary papillary renal carcinoma; VHL;

D O I：

10.1016/j.ucl.2008.07.014

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Hereditary and familial forms of kidney cancer are encountered routinely in urologic practice. Discoveries in the genetic and molecular biology of these diseases have had a critical impact on the understanding of kidney cancer pathogenesis in nearly all subtypes of renal cortical neoplasms and their clinical features. Developing knowledge in the field has helped formulate new diagnostic and molecular therapeutic strategies for patients who have kidney cancer. This article aims to familiarize the reader with the current understanding of identified syndromes, their biology, and approaches to treatment.

引用

收藏

页码：563 / 572

页数：10

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