Oncocytic carcinoid tumor of the lung with intense F-18 fluorodeoxyglucose (FDG) uptake in positron emission tomography-computed tomography (PET/CT)

被引：8

作者：

Tanabe, Yuki ^{[1
]}

Sugawara, Yoshifumi ^{[1
]}

Nishimura, Rieko ^{[2
]}

Hosokawa, Kohei ^{[1
]}

Kajihara, Makoto ^{[1
]}

Shimizu, Teruhiko ^{[1
]}

Takahashi, Tadaaki ^{[1
]}

Sakai, Shinya ^{[1
]}

Sawada, Shigeki ^{[3
]}

Yamashita, Motohiro ^{[3
]}

Ohtani, Haruhiko ^{[4
]}

机构：

[1] Natl Hosp Org, Shikoku Canc Ctr, Dept Diagnost Radiol, Matsuyama, Ehime 7910280, Japan

[2] Natl Hosp Org, Shikoku Canc Ctr, Dept Clin Lab, Matsuyama, Ehime 7910280, Japan

[3] Natl Hosp Org, Shikoku Canc Ctr, Dept Thorac Surg, Matsuyama, Ehime 7910280, Japan

[4] Saiseikai Saijo Hosp, Dept Radiol, Saijo, Ehime, Japan

来源：

ANNALS OF NUCLEAR MEDICINE | 2013年 / 27卷 / 08期

关键词：

Oncocytic carcinoid tumor; FDG; PET/CT; GLUT-1; Mitochondria; PULMONARY NEUROENDOCRINE TUMORS; GLUT1; EXPRESSION;

D O I：

10.1007/s12149-013-0738-0

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

The present report describes a case of typical carcinoid tumor with intense fluorodeoxyglucose (FDG) uptake. The most of tumor cells were characterized by eosinophilic cytoplasm resulting from accumulation of mitochondria, which was called an oncocytic carcinoid tumor. Glucose transporter type 1 (GLUT-1) was expressed in a membranous pattern in the oncocytic component. Oncocytic carcinoid tumors could show intense FDG uptake due to the numerous intracellular mitochondria and the membranous overexpression of GLUT-1. Thus, it could be a potential pitfall of interpreting FDG-PET/CT image.

引用

页码：781 / 785

页数：5

共 17 条

[1]

CHANG A, 1992, PATHOL ANNU, V27, P263

[2] Integrated PET/CT of pulmonary neuroendocrine tumors: Diagnostic and prognostic implications [J].

Chong, Semin ;

Lee, Kyung Soo ;

Kim, Byung-Tae ;

Choi, Joon Young ;

Yi, Chin A. ;

Chung, Myung Jin ;

Oh, Dae-Kun ;

Lee, Ji-Young .

AMERICAN JOURNAL OF ROENTGENOLOGY, 2007, 188 (05) :1223-1231

[3]

Chung JH, 2004, J NUCL MED, V45, P999

[4] Evaluation of primary pulmonary carcinoid tumors using FDG PET [J].

Erasmus, JJ ;

McAdams, HP ;

Patz, EF ;

Coleman, RE ;

Ahuja, V ;

Goodman, PC .

AMERICAN JOURNAL OF ROENTGENOLOGY, 1998, 170 (05) :1369-1373

[5] Typical and atypical carcinoid tumours:: analysis of the experience of the Spanish Multi-centric Study of Neuroendocrine Tumours of the Lung [J].

Garcia-Yuste, Mariano ;

Matilla, Jose M. ;

Cueto, Antonio ;

Rodriguez Paniagua, Jose Manuel ;

Ramos, Guillermo ;

Canizares, Miguel Angel ;

Muguruza, Ignacio .

EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 2007, 31 (02) :192-197

[6] A case of pulmonary typical carcinoid with an extensive oncocytic component showing intense uptake of FDG [J].

Kadowaki, Toru ;

Yano, Shuichi ;

Araki, Kunio ;

Tokushima, Takeshi ;

Morioka, Nobuo .

THORAX, 2011, 66 (04) :361-362

[7] Immunohistochemical staining of GLUT1 in benign, borderline, and malignant ovarian epithelia [J].

Kalir, T ;

Wang, BY ;

Goldfischer, M ;

Haber, RS ;

Reder, I ;

Demopoulos, R ;

Cohen, CJ ;

Burstein, DE .

CANCER, 2002, 94 (04) :1078-1082

[8] Sensitivity of FDG PET, GLUT1 expression and proliferative index in bronchioloalveolar lung cancer [J].

Khandani, Amir H. ;

Whitney, Kathleen D. ;

Keller, Steven M. ;

Isasi, Carmen R. ;

Blaufox, M. Donald .

NUCLEAR MEDICINE COMMUNICATIONS, 2007, 28 (03) :173-177

[9] Use of integrated FDG PET/CT imaging in pulmonary carcinoid tumours [J].

Kruger, S. ;

Buck, A. K. ;

Blumstein, N. M. ;

Pauls, S. ;

Schelzig, H. ;

Kropf, C. ;

Schumann, C. ;

Mottaghy, F. M. ;

Hombach, V. ;

Reske, S. N. .

JOURNAL OF INTERNAL MEDICINE, 2006, 260 (06) :545-550

[10] Differential Expression of Glut1 in Pulmonary Neuroendocrine Tumors: Correlation with Histological Grade [J].

Lee, Hyun Ju ;

Yoo, Seol Bong ;

Lee, Won Woo ;

Chung, Doo Hyun ;

Seo, Jeong-Wook ;

Chung, Jin-Haeng .

KOREAN JOURNAL OF PATHOLOGY, 2009, 43 (03) :201-205

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