Plasticity in passive cell mechanics

被引：3

作者：

Ambrosi, D. ^{[1
]}

Ciarletta, P. ^{[2
,3
,4
]}

机构：

[1] Politecn Milan, Dipartimento Matemat, MOX, I-20133 Milan, Italy

[2] Univ Paris 06, CNRS, F-75005 Paris, France

[3] Univ Paris 06, Inst Jean le Rond dAlembert, UMR 7190, F-75005 Paris, France

[4] Ctr Europe Nanomed, CEN, I-20133 Milan, Italy

来源：

INTERNATIONAL JOURNAL OF NON-LINEAR MECHANICS | 2013年 / 56卷

关键词：

Living cell; Visco-elasto-plasticity; Cell mechanics; Plastic hardening; DYNAMICS; MODEL;

D O I：

10.1016/j.ijnonlinmec.2013.04.007

中图分类号：

O3 [力学];

学科分类号：

08 ; 0801 ;

摘要：

A sufficiently large load applied to a living cell for a sufficiently long time produces a deformation which is not entirely recoverable by passive mechanisms. This kind of plastic behavior is well documented by experiments but it is still seldom investigated in terms of mechanical theories. Here we discuss a finite visco-elasto-plastic model where the rest elongation of the cell evolves in time as a function of the dissipated energy at a microstructural level. The theoretical predictions of the proposed model reproduce, also in quantitative terms, the passive mechanics of optically stretched cells. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：56 / 60

页数：5

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