Incidental versus clinically evident thyroid cancer: A 5-year follow-up study

被引：7

作者：

Minuto, Michele N. ^{[1
]}

Miccoli, Mario ^{[2
]}

Viola, David ^{[3
]}

Ugolini, Clara ^{[1
]}

Giannini, Riccardo ^{[1
]}

Torregrossa, Liborio ^{[1
]}

Antonangeli, Lucia ^{[3
]}

Aghini-Lombardi, Fabrizio ^{[3
]}

Elisei, Rossella ^{[3
]}

Basolo, Fulvio ^{[1
]}

Miccoli, Paolo ^{[1
]}

机构：

[1] Univ Pisa, Dept Surg, I-56124 Pisa, Italy

[2] Univ Pisa, Dept Expt Pathol MBIE, I-56124 Pisa, Italy

[3] Univ Pisa, Dept Endocrinol, I-56124 Pisa, Italy

来源：

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2013年 / 35卷 / 03期

关键词：

incidental thyroid cancer; differentiated thyroid cancer; preoperative diagnosis; thyroidectomy; follow-up; LYMPH-NODE DISSECTION; PAPILLARY CARCINOMA; MANAGEMENT;

D O I：

10.1002/hed.22974

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

Background. The incidence of differentiated thyroid cancer in patients undergoing surgery for presumed benign thyroid disease (incidental thyroid cancer) is not negligible. The purpose of this study was to verify if incidental thyroid cancers have a different clinical course than the clinically evident thyroid cancer. Methods. A group of patients with incidental thyroid cancer (n = 95) has been compared to a control group with clinically evident thyroid cancer (n = 93). Both the histology and the outcome after a 5-year follow-up have been compared. Results. At the univariate analysis, the groups demonstrated significant differences in many pathologic features, remnant ablation (p < .001), and persistent disease (p = .006). Nevertheless, the multivariate analysis revealed that the outcome was not influenced by the preoperative or the incidental diagnosis. Conclusion. Incidental thyroid cancers show a different pathological pattern when compared to clinically evident thyroid cancers. Nonetheless, the final outcome is not influenced by preoperative or postoperative diagnosis. Hence, patients with incidental thyroid cancer should follow the same postoperative protocols of patients with clinically evident thyroid cancer. (C) 2012 Wiley Periodicals, Inc. Head Neck 35: 408-412, 2013

引用

页码：408 / 412

页数：5

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