Temperature distribution analysis of tissue water vaporization during microwave ablation: Experiments and simulations

被引:37
作者
Ai, Haiming [1 ]
Wu, Shuicai [1 ]
Gao, Hongjian [1 ]
Zhao, Lei [1 ]
Yang, Chunlan [1 ]
Zeng, Yi [1 ]
机构
[1] Beijing Univ Technol, Coll Life Sci & Bioengn, Ctr Biomed Engn, Beijing 100124, Peoples R China
关键词
Enthalpy; microwave ablation; SAR; temperature field; water vaporisation; THERMAL ABLATION; LIVER-CANCER; EX-VIVO; COAGULATION; ULTRASOUND; THERAPY; ANTENNA; SAR; RADIOFREQUENCY; HYPERTHERMIA;
D O I
10.3109/02656736.2012.710769
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The temperature distribution in the region near a microwave antenna is a critical factor that affects the entire temperature field during microwave ablation of tissue. It is challenging to predict this distribution precisely, because the temperature in the near-antenna region varies greatly. The effects of water vaporisation and subsequent tissue carbonisation in an ex vivo porcine liver were therefore studied experimentally and in simulations. The enthalpy and high-temperature specific absorption rate (SAR) of liver tissues were calculated and incorporated into the simulation process. The accuracy of predictions for near-field temperatures in our simulations has reached the level where the average maximum error is less than 5 degrees C. In addition, a modified thermal model that accounts for water vaporisation and the change in the SAR distribution pattern is proposed and validated with experiment. The results from this study may be useful in the clinical practice of microwave ablation and can be applied to predict the temperature field in surgical planning.
引用
收藏
页码:674 / 685
页数:12
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