Selective detection of bacteria in urine with a long-range surface plasmon waveguide biosensor

被引：30
作者：
Beland, Paul [1 ]
Krupin, Oleksiy [2 ]
Berini, Pierre [3 ,4 ,5 ]
机构：
[1] Univ Ottawa, Dept Biomed Engn, Ottawa, ON K1N 6N5, Canada
[2] Univ Ottawa, Dept Biol & Chem Engn, Ottawa, ON K1N 6N5, Canada
[3] Univ Ottawa, Sch Elect Engn & Comp Sci, Ottawa, ON K1N 6N5, Canada
[4] Univ Ottawa, Dept Phys, Ottawa, ON K1N 6N5, Canada
[5] Univ Ottawa, Ctr Res Photon, Ottawa, ON K1N 6N5, Canada
来源：
BIOMEDICAL OPTICS EXPRESS | 2015年 / 6卷 / 08期
关键词：
RESONANCE; DIAGNOSIS; FABRICATION; INFECTION; CYTOP;
D O I：
10.1364/BOE.6.002908
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Experimentation demonstrates long-range surface plasmon polariton waveguides as a useful biosensor to selectively detect gram negative or gram positive bacteria in human urine having a low concentration of constituents. The biosensor can detect bacteria at concentrations of 10(5) CFU/ml, the internationally recommended threshold for diagnostic of urinary tract infection. Using a negative control urine solution of bacterial concentration 1000 x higher than the targeted bacteria, we obtain a ratio of 5.4 for the positive to negative signals. (C) 2015 Optical Society of America
引用
收藏
页码：2908 / 2922
页数：15
相关论文
共 22 条
[1]  
[Anonymous], J LIGHTWAVE IN PRESS
[2]  
[Anonymous], 1971, COMPOSITION CONCENTR
[3]   Long-range surface plasmon polaritons [J].
Berini, Pierre .
ADVANCES IN OPTICS AND PHOTONICS, 2009, 1 (03) :484-588
[4]   Long-range surface plasmon-polariton mode cutoff and radiation in embedded strip waveguides [J].
Breukelaar, Ian ;
Charbonneau, Robert ;
Berini, Pierre .
JOURNAL OF APPLIED PHYSICS, 2006, 100 (04)
[5]   Screening for Urinary Tract Infection with the Sysmex UF-1000i Urine Flow Cytometer [J].
Broeren, Maarten A. C. ;
Bahceci, Semiha ;
Vader, Huib L. ;
Arents, Niek L. A. .
JOURNAL OF CLINICAL MICROBIOLOGY, 2011, 49 (03) :1025-1029
[6]   Long range surface plasmon resonance for increased sensitivity in living cell biosensing through greater probing depth [J].
Chabot, Vincent ;
Miron, Yannick ;
Grandbois, Michel ;
Charette, Paul G. .
SENSORS AND ACTUATORS B-CHEMICAL, 2012, 174 :94-101
[7]   Fabrication of surface plasmon waveguides and devices in Cytop with integrated microfluidic channels [J].
Chiu, Charles ;
Lisicka-Skrzek, Ewa ;
Tait, R. Niall ;
Berini, Pierre .
JOURNAL OF VACUUM SCIENCE & TECHNOLOGY B, 2010, 28 (04) :729-735
[8]   Surface plasmon resonance immunosensor for human cardiac troponin T based on self-assembled monolayer [J].
Dutra, Rosa Fireman ;
Mendes, Renata Kelly ;
da Silva, Valdinete Lins ;
Kubota, Lauro Tatsuo .
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2007, 43 (05) :1744-1750
[9]   Detection of Escherichia coli O157:H7 using a surface plasmon resonance biosensor [J].
Fratamico, PM ;
Strobaugh, TP ;
Medina, MB ;
Gehring, AG .
BIOTECHNOLOGY TECHNIQUES, 1998, 12 (07) :571-576
[10]   Fabrication of long-range surface plasmon-polariton Bragg gratings with microfluidic channels in Cytop claddings [J].
Hassan, Sa'ad ;
Khodami, Maryam ;
Tait, R. Niall ;
Berini, Pierre .
MICROELECTRONIC ENGINEERING, 2015, 135 :38-44
123