Reversible two-photon fluorescent probe for imaging of hypochlorous acid in live cells and in vivo

被引：2
|
作者：
Zhang, Wei [1 ]
Liu, Wei [1 ]
Li, Ping [1 ]
Kang, Junqing [1 ]
Wang, Jiaoyang [1 ]
Wang, Hui [1 ]
Tang, Bo [1 ]
机构：
[1] Shandong Normal Univ, Coll Chem Chem Engn & Mat Sci, Collaborat Innovat Ctr Funct Probes Chem Imaging, Key Lab Mol & Nano Probes,Minist Educ,Shandong Un, Jinan 250014, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 50期
基金：
中国国家自然科学基金;
关键词：
REACTIVE OXYGEN; CANCER-CELLS; LUMINESCENT PROBES; OXIDATIVE STRESS; LIVING CELLS; MYELOPEROXIDASE; PEROXYNITRITE; TISSUE; ROS;
D O I：
10.1039/C5CC02537K
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Herein, we have developed a novel reversible two-photon fluorescent probe that is well suited for monitoring HOCl levels selectively and instantaneously. Results showed the reversible and instantaneous responses of the probe towards intracellular HOCl. Moreover, the probe was successfully applied to the imaging of the HOCl levels in zebrafish and mice via two-photon imaging.
引用
收藏
页码：10150 / 10153
页数：4
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