STABILITY OF A NON-LOCAL KINETIC MODEL FOR CELL MIGRATION WITH DENSITY DEPENDENT ORIENTATION BIAS

The aim of the article is to study the stability of a non-local kinetic model proposed in [17], that is a kinetic model for cell migration taking into account the non-local sensing performed by a cell in order to decide its direction and speed of movement. We show that pattern formation results from modulation of one non-dimensional parameter that depends on the tumbling frequency, the sensing radius, the mean speed in a given direction, the uniform configuration density and the tactic response to the cell density. Numerical simulations show that our linear stability analysis predicts quite precisely the ranges of parameters determining instability and pattern formation. We also extend the stability analysis to the case of different mean speeds in different directions.