The complexation of aqueous metal ions relevant to biological applications. 1. Poorly soluble zinc salts and enhanced solubility with added amino acid

被引：6

作者：

Sobel, Sabrina ^{[1
]}

Haigney, Allison ^{[1
]}

Concepcion, Tracy ^{[1
]}

Kim, Michael ^{[1
]}

机构：

[1] Hofstra Univ, Dept Chem, Hempstead, NY 11549 USA

来源：

CHEMICAL SPECIATION AND BIOAVAILABILITY | 2008年 / 20卷 / 02期

关键词：

zinc; amino acids; complexation; solubility;

D O I：

10.3184/095422908X322833

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The effect of added amino acid (glycine, alanine and serine) on the solubility of zinc citrate, zinc succinate and zinc oxalate was investigated. Equilibrated solutions were prepared and titrated to endpoint at pH 5.5 with Na(2)EDTA using Xylenol Orange indicator. In every case, a significant enhancement in solubility was seen as the amino acid increased from 1 to 50 molar excess. The increase was non-linear, and, with zinc succinate, showed saturation effects. In these cases, solution composition may be more complicated than initially thought, including mixed-ligand complexes and increasing percent free metal ion as the proportion of amino acid increases.

引用

页码：93 / 97

页数：5

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