Single molecule imaging using X-ray free electron lasers

被引：13
作者：
Barty, Anton [1 ]
机构：
[1] Deutsch Elektronen Synchrotron DESY, Ctr Free Electron Laser Sci, Notkestr 85, D-22607 Hamburg, Germany
来源：
CURRENT OPINION IN STRUCTURAL BIOLOGY | 2016年 / 40卷
关键词：
SERIAL FEMTOSECOND CRYSTALLOGRAPHY; RADIATION-DAMAGE; STRUCTURAL DYNAMICS; ATOMIC-STRUCTURE; CRYO-EM; DIFFRACTION; SYNCHROTRON; SCATTERING; SPARSE;
D O I：
10.1016/j.sbi.2016.11.017
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The potential to image single molecules in action without the need for crystallisation was one of the most exciting applications promised during construction of the first XFELs. Over the past years significant progress has been made, even though the goal of molecular imaging has not yet been achieved. This article reviews the current status, and the steps required to realise X-ray single particle imaging.
引用
收藏
页码：186 / 194
页数：9
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