SYNTHESIS AND CHARACTERIZATION OF SOME NOVEL 2-HYDROXY-N-(2-TRIFLUOROMETHYL-PHENYL)-BENZAMIDE DERIVATIVES

被引:0
|
作者
Ienascu, Ioana M. C. [1 ]
Lupea, Alfa X. [1 ]
Popescu, Iuliana M. [2 ]
Mosoarca, Cristina [3 ]
Zamfir, Alina D. [3 ,4 ]
机构
[1] Polytech Univ, Fac Ind Chem & Environm Engn, Dept Organ Chem, Timisoara 300006, Romania
[2] Banats Agr Sci Univ, Fac Agr, Dept Chem & Biochem, Timisoara 300645, Romania
[3] Natl Inst Res & Dev Electrochem & Condensed Matte, Mass Spectrometry Lab, Timisoara 300224, Romania
[4] Aurel Vlaicu Univ Arad, Arad 310130, Romania
关键词
2-hydroxy-N-(2-trifluoromethyl-phenyl)-benzamide derivatives; ethyl esters; hydrazides; hydrazones; salicylanilide-O-substituted;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
In order to obtain biological active compounds, the synthesis of some new derivatives with o-hidroxibenzamidic structure was achieved, Starting from 2-hydroxy-N-(2-trifluoromethyl-phenyl)-benzamide and ethyl alpha-halogenated acid esters were obtained ethyl esters, which were condensated with hydrazine giving hydrazides. In reaction between hydrazides and chloro-substituted benzaldehydes were obtained hydrazones. All new synthesized compounds were characterized by physico-chemical methods (FTIR, H-1-NMR, C-13-NMR, MS), which confirmed their Structures.
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页码:273 / +
页数:5
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