Feline Foamy Virus is Highly Prevalent in Free-Ranging Puma concolor from Colorado, Florida and Southern California

被引：11

作者：

Kechejian, Sarah R. ^{[1
]}

Dannemiller, Nick ^{[1
]}

Kraberger, Simona ^{[2
]}

Ledesma-Feliciano, Carmen ^{[3
]}

Malmberg, Jennifer ^{[4
]}

Roelke Parker, Melody ^{[5
]}

Cunningham, Mark ^{[6
]}

McBride, Roy ^{[7
]}

Riley, Seth P. D. ^{[8
]}

Vickers, Winston T. ^{[9
]}

Logan, Ken ^{[10
]}

Alldredge, Mat ^{[11
]}

Crooks, Kevin ^{[12
]}

Loechelt, Martin ^{[13
]}

Carver, Scott ^{[14
]}

VandeWoude, Sue ^{[1
]}

机构：

[1] Colorado State Univ, Coll Vet Med & Biomed Sci, Dept Microbiol Immunol & Pathol, Ft Collins, CO 80523 USA

[2] Arizona State Univ, Biodesign Inst, Tempe, AZ 85281 USA

[3] Univ Colorado, Div Infect Dis, Anschutz Med Campus,12700 E 19th Ave, Aurora, CO 80045 USA

[4] Univ Wyoming, Wyoming State Vet Lab, 1174 Snowy Range Rd, Laramie, WY 82072 USA

[5] Leidos Biomed Res Inc, Frederick Natl Lab Canc Res, Frederick, MD 21701 USA

[6] Florida Fish & Wildlife Conservat Commiss, 1105 SW Williston Rd, Gainesville, FL 32601 USA

[7] Ranchers Supply Inc, Alpine, TX 79830 USA

[8] Natl Pk Serv, Santa Monica Mt Natl Recreat Area, Thousand Oaks, CA 90265 USA

[9] Univ Calif Davis, Karen C Drayer Wildlife Hlth Ctr, Davis, CA 95616 USA

[10] Colorado Pk & Wildlife, 2300 S Townsend Ave, Montrose, CO 80203 USA

[11] Colorado Div Wildlife Off, Mammals Res, 317 W Prospect Rd, For Collins, CO 80526 USA

[12] Colorado State Univ, Dept Fish Wildlife & Conservat Biol, 115 Wagar, Ft Collins, CO 80523 USA

[13] Deutsch Krebsforschungszentrum Heidelberg DKFZ, German Canc Res Ctr, Res Program Infect Inflammat & Canc, Dept Mol Diagnost Oncogen Infect, Neuenheimer Feld 242, D-69120 Heidelberg, Germany

[14] Univ Tasmania, Sch Biol Sci, Sandy Bay, Tas 7005, Australia

来源：

VIRUSES-BASEL | 2019年 / 11卷 / 04期

基金：

美国国家科学基金会;

关键词：

feline foamy virus; epidemiology; retrovirus; Spumaretrovirus; mountain lion; Puma concolor; ELISA; SEROEPIDEMIOLOGICAL SURVEY; RETROVIRUS INFECTIONS; CATS; PROTEINS;

D O I：

10.3390/v11040359

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Feline foamy virus (FFV) is a retrovirus that has been detected in multiple feline species, including domestic cats (Felis catus) and pumas (Puma concolor). FFV results in persistent infection but is generally thought to be apathogenic. Sero-prevalence in domestic cat populations has been documented in several countries, but the extent of viral infections in nondomestic felids has not been reported. In this study, we screened sera from 348 individual pumas from Colorado, Southern California and Florida for FFV exposure by assessing sero-reactivity using an FFV anti-Gag ELISA. We documented a sero-prevalence of 78.6% across all sampled subpopulations, representing 69.1% in Southern California, 77.3% in Colorado, and 83.5% in Florida. Age was a significant risk factor for FFV infection when analyzing the combined populations. This high prevalence in geographically distinct populations reveals widespread exposure of puma to FFV and suggests efficient shedding and transmission in wild populations.

引用

页数：9

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