Vitamin D for inflammation biomarkers in coronary artery disease A protocol for systematic review and meta-analysis

被引:2
作者
Wang, Yiru [1 ]
Zhang, Yifan [1 ]
Wei, Jing [2 ]
Du, Wenting [1 ]
Ding, Jie [1 ]
Zhang, Yiyi [1 ]
Zhang, Na [1 ]
Mao, Meijiao [1 ]
Liu, Ping [1 ]
机构
[1] Shanghai Univ Tradit Chinese Med, Longhua Hosp, 725 South Wan Ping Rd, Shanghai 200032, Peoples R China
[2] Shanghai Xuhui Cent Hosp, Dept Tradit Chinese Med, Shanghai, Peoples R China
关键词
vitamin D; inflammation; coronary artery disease; review; meta-analysis; CARDIOVASCULAR-DISEASE; HEART-DISEASE; UPDATE; MANAGEMENT;
D O I
10.1097/MD.0000000000021407
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Coronary artery disease (CAD) is a clinically common coronary heart disease. Vitamin D might be beneficial in CAD patients through its favorable effects on inflammation biomarkers. This study will be performed to examine the effects of Vitamin D supplementation on inflammatory markers in CAD patients. Methods: We will search the electronical databases and hand-searching journals or reference lists. The study screening and data extraction will be carried out by 2 investigators independently. The primary outcome is inflammatory biomarkers of peripheral blood. Secondary outcomes are triglyceride, total cholesterol, high-density lipoprotein cholesterol levels, low-density lipoprotein cholesterol, and blood pressure. Review Manager (RevMan, version 5.3; The Nordic Cochrane Centre, Copenhagen, Denmark:) V.5.3 software will be used to compute the data. Results: The results of the study will provide a reliable evidence to assess the efficacy of Vitamin D supplement on inflammation biomarkers of CAD patients. Conclusion: The conclusion of our systematic review will answer whether Vitamin D is an effective intervention to relieve inflammation of CAD patients.
引用
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页数:5
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