A case of ALK-rearranged lung adenocarcinoma associated with syndrome of inappropriate antidiuretic hormone

被引：0

作者：

Miyashita, Yoshihiro ^{[1
]}

Hanawa, Kotaro ^{[1
]}

Kobayashi, Hiroaki ^{[1
]}

Kumagai, Takashi ^{[1
]}

Inomata, Kie ^{[1
]}

Tsutsui, Toshiharu ^{[1
]}

Kakizaki, Yumiko ^{[1
]}

Oyama, Toshio ^{[2
]}

机构：

[1] Yamanashi Prefectural Cent Hosp, Dept Pulm Med, 1-1-1 Fujimi, Kofu, Yamanashi, Japan

[2] Yamanashi Prefectural Cent Hosp, Dept Pathol, Kofu, Yamanashi, Japan

来源：

RESPIRATORY MEDICINE CASE REPORTS | 2020年 / 30卷

关键词：

ALK; SIADH; Hyponatremia; Crizotinib; Lung adenocarcinoma; CANCER; CRIZOTINIB; SECRETION; SIADH;

D O I：

10.1016/j.rmcr.2020.101136

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

A 60-year-old man with a history of smoking was transferred to our hospital for consciousness disorder. A diagnosis of ALK-rearranged lung adenocarcinoma associated with a paraneoplastic electrolytic disorder was made following a cutaneous needle biopsy. Both the primary lung lesion and multiple metastases shrunk and his electrolytic disorder resolved after the introduction of a first-line molecular-targeted drug chemotherapy with crizotinib. We herein report a case of ALK-rearranged lung adenocarcinoma accompanied by SIADH, successfully treated with crizotinib.

引用

页数：4

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