The functions of kinesin and kinesin-related proteins in eukaryotes

被引:55
|
作者
Ali, Iftikhar [1 ]
Yang, Wei-Cai [1 ,2 ]
机构
[1] Chinese Acad Sci, Inst Genet & Dev Biol, State Key Lab Mol Dev Biol, Beijing 100101, Peoples R China
[2] Univ Chinese Acad Sci, Coll Adv Agr Sci, Beijing, Peoples R China
关键词
Kinesins; microtubule; motor domain; cargoes; cellular organelles; PLANT-SPECIFIC KINESIN; F-ACTIN ORGANIZATION; CORTICAL MICROTUBULES; CELLULOSE SYNTHASE; PLASMA-MEMBRANE; SKELETAL-MUSCLE; CHLOROPLAST MOVEMENT; CHROMOKINESIN KID; ARABIDOPSIS ROOT; SPINDLE POSITION;
D O I
10.1080/19336918.2020.1810939
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Kinesins constitute a superfamily of ATP-driven microtubule motor enzymes that convert the chemical energy of ATP hydrolysis into mechanical work along microtubule tracks. Kinesins are found in all eukaryotic organisms and are essential to all eukaryotic cells, involved in diverse cellular functions such as microtubule dynamics and morphogenesis, chromosome segregation, spindle formation and elongation and transport of organelles. In this review, we explore recently reported functions of kinesins in eukaryotes and compare their specific cargoes in both plant and animal kingdoms to understand the possible roles of uncharacterized motors in a kingdom based on their reported functions in other kingdoms.
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页码:139 / 152
页数:14
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