Primary Signet-ring Cell Carcinoma of the Urinary Bladder A Clinicopothologic and Immunohistochemical Study of 5 Cases

被引：18

作者：

Del Sordo, Rachele ^{[1
]}

Bellezza, Guido ^{[1
]}

Colella, Renato ^{[1
]}

Mameli, Maria Grazia ^{[1
]}

Sidoni, Angelo ^{[1
]}

Cavaliere, Antonio ^{[1
]}

机构：

[1] Univ Perugia, Inst Pathol Anat & Histol, I-06100 Perugia, Italy

来源：

APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY | 2009年 / 17卷 / 01期

关键词：

signet-ring cell carcinoma; secondary tumors; immunohistochemistry; PRIMARY ADENOCARCINOMA; CYSTITIS-GLANDULARIS; CLONE; 34-BETA-E12; PRIMARY TUMORS; PROSTATE; DIFFERENTIATION; DISTINCTION; EXPRESSION; NEOPLASMS; DIAGNOSIS;

D O I：

10.1097/PAI.0b013e31816a7466

中图分类号：

R602 [外科病理学、解剖学]; R32 [人体形态学];

学科分类号：

100101 ;

摘要：

Primary signet-ring cell carcinoma of the urinary bladder is a rare histologic variant of adenocarcinoma. Generally, this neoplasm occurs in middle age and the clinical presentation does not differ from the most frequent transitional cell carcinomas. The prognosis is frequently poor as at diagnosis it is often in an advanced phase. It is essential to distinguish this carcinoma from metastases, as different therapeutic strategies are often necessary. We present 5 cases of primary signet-ring cell carcinoma of the urinary bladder and we used a panel of histochemical and immunohistochemical markers for differential diagnosis from secondary carcinoma in an attempt to elucidate the histogenetic derivation of this neoplasia.

引用

页码：18 / 22

页数：5

共 41 条

[1] PRIMARY ADENOCARCINOMAS OF THE HUMAN URINARY-BLADDER - HISTOCHEMICAL, IMMUNOLOGICAL AND ULTRASTRUCTURAL STUDIES [J].