Interaction between remnant-like lipoprotein particles and adipocytes

被引：0
作者：
Zheng, Xiao-Yan
Liu, Ling
Yang, De-Guang
机构：
来源：
INTERNATIONAL JOURNAL OF CARDIOLOGY | 2009年 / 133卷 / 01期
基金：
中国国家自然科学基金;
关键词：
Remnant-like lipoprotein particles; Triglyceride-rich lipoproteins; Adipocytes; Inflammation; LOW-DENSITY-LIPOPROTEIN; NECROSIS-FACTOR-ALPHA; FACTOR-KAPPA-B; ADIPOSE-SPECIFIC PROTEIN; ENDOTHELIAL-CELLS; INSULIN-RESISTANCE; LIPID-METABOLISM; GENE-EXPRESSION; GROWTH-HORMONE; ADIPONECTIN;
D O I：
10.1016/j.ijcard.2008.10.027
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Inflammation plays a pivotal role in the pathophysiology of atherosclerosis. Remnant-like lipoprotein particles (RLPs) have been implicated as potentially atherogenic lipoproteins. RLPs can induce a pronounced inflammatory response especially during the postprandial phase. Increasing evidence demonstrates that adipose tissue may be a significant contributor to the increased systemic inflammation through secretion of various proinflammatory adipocytokines. In addition, adipocytes may potentially regulate RLPs metabolism. Therefore, we hypothesized that there might be an interaction between RLPs and adipocytes. (C) 2008 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：3 / 7
页数：5
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