Multifunctional Hybrid Materials From Poly(3-Hydroxybutyrate), TiO2 Nanoparticles, and Chitosan Oligomers by Combining Electrospinning/Electrospraying and Impregnation

被引:41
作者
Korina, Elena [1 ]
Stoilova, Olya [1 ]
Manolova, Nevena [1 ]
Rashkov, Iliya [1 ]
机构
[1] Bulgarian Acad Sci, Inst Polymers, Lab Bioact Polymers, BG-1113 Sofia, Bulgaria
关键词
chitosan; electrospinning; fibers; poly(3-hydroxybutyrate); titanium dioxide nanoparticles; IN-VITRO BIOCOMPATIBILITY; ELECTROSPUN; SURFACE; BEHAVIOR; FIBERS; FILMS;
D O I
10.1002/mabi.201200410
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Several types of fibrous material containing poly(3-hydroxybutyrate) (PHB), nanosized TiO2-anatase (nanoTiO2), and chitosan oligomers are prepared by combining the electrospinning, electrospraying, and impregnation techniques. Simultaneous electrospinning/electrospraying provides uniform distribution of electrosprayed nanoTiO2 along the PHB fibers and throughout the mat. Hybrid materials of different design manifest excellent photocatalytic activity, even after repeated use. They exhibit high bactericidal activity against Escherichia coli. In addition, the fibrous scaffolds are compatible with human mesenchymal stem cells and provide a favorable environment for their development.
引用
收藏
页码:707 / 716
页数:10
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