Attachment of adeno-associated virus type 3H to fibroblast growth factor receptor 1

被引：39

作者：

Blackburn, SD ^{[1
]}

Steadman, RA ^{[1
]}

Johnson, FB ^{[1
]}

机构：

[1] Brigham Young Univ, Dept Mol Biol & Microbiol, Provo, UT 84602 USA

来源：

ARCHIVES OF VIROLOGY | 2006年 / 151卷 / 03期

关键词：

D O I：

10.1007/s00705-005-0650-6

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Heparan sulfate proteoglycan is thought to act as primary receptor for adeno-associated virus type 2 (AAV-2). Reported coreceptors include alpha V beta 5 integrin, fibroblast growth factor receptor 1 (FGFR-1), and hepatocyte growth factor (c-Met). The interaction of AAV type 3 (AAV-3) with possible cell membrane receptors is incompletely defined. In this study, using assays detecting competition with viral infection, virus binding inhibition assays and dot blotting, we show attachment of AAV-3 strain H to heparin, heparan sulfate, and FGFR-1. These findings provide new information on the possible receptor array used by AAV-3.

引用

页码：617 / 623

页数：7

共 14 条

[1] Identification of PDGFR as a receptor for AAV-5 transduction [J].

Di Pasquale, G ;

Davidson, BL ;

Stein, CS ;

Martins, IS ;

Scudiero, D ;

Monks, A ;

Chiorini, JA .

NATURE MEDICINE, 2003, 9 (10) :1306-1312

[2] A parvovirus isolated from royal python']python (Python']Python regius) is a member of the genus Dependovirus [J].

Farkas, SL ;

Zádori, Z ;

Benko, M ;

Essbauer, S ;

Harrach, B ;

Tijssen, P .

JOURNAL OF GENERAL VIROLOGY, 2004, 85 :555-561

[3] Adeno-associated virus (AAV)-3-based vectors transduce haematopoietic cells not susceptible to transduction with AAV-2-based vectors [J].

Handa, A ;

Muramatsu, S ;

Qiu, JM ;

Mizukami, H ;

Brown, KE .

JOURNAL OF GENERAL VIROLOGY, 2000, 81 :2077-2084

[4] Attachment of bovine parvovirus to sialic acids on bovine cell membranes [J].

Johnson, FB ;

Fenn, LB ;

Owens, TJ ;

Faucheux, LJ ;

Blackburn, SD .

JOURNAL OF GENERAL VIROLOGY, 2004, 85 :2199-2207

[5] Adeno-associated virus serotype 4 (AAV4) and AAV5 both require sialic acid binding for hemagglutination and efficient transduction but differ in sialic acid linkage specificity [J].

Kaludov, N ;

Brown, KE ;

Walters, RW ;

Zabner, J ;

Chiorini, JA .

JOURNAL OF VIROLOGY, 2001, 75 (15) :6884-6893

[6] Hepatocyte growth factor receptor is a coreceptor for adeno-associated virus type 2 infection [J].

Kashiwakura, Y ;

Tamayose, K ;

Iwabuchi, K ;

Hirai, Y ;

Shimada, T ;

Matsumoto, K ;

Nakamura, T ;

Watanabe, M ;

Oshimi, K ;

Daida, H .

JOURNAL OF VIROLOGY, 2005, 79 (01) :609-614

[7] Identification of a heparin-binding motif on adeno-associated virus type 2 capsids [J].

Kern, A ;

Schmidt, K ;

Leder, C ;

Müller, OJ ;

Wobus, CE ;

Bettinger, K ;

Von der Lieth, CW ;

King, JA ;

Kleinschmidt, JA .

JOURNAL OF VIROLOGY, 2003, 77 (20) :11072-11081

[8] Evolutionary relationships among parvoviruses: Virus-host coevolution among autonomous primate parvoviruses and links between adeno-associated and avian parvoviruses [J].

Lukashov, VV ;

Goudsmit, J .

JOURNAL OF VIROLOGY, 2001, 75 (06) :2729-2740

[9] Human fibroblast growth factor receptor 1 is a co-receptor for infection by adeno-associated virus 2 [J].

Qing, K ;

Mah, C ;

Hansen, J ;

Zhou, SZ ;

Dwarki, V ;

Srivastava, A .

NATURE MEDICINE, 1999, 5 (01) :71-77

[10] The interaction of heparin sulfate and adeno-associated virus 2 [J].

Qiu, JM ;

Handa, A ;

Kirby, M ;

Brown, KE .

VIROLOGY, 2000, 269 (01) :137-147

← 1 2 →