Contemporary Medical Management of Acute Severe Ulcerative Colitis

被引：21

作者：

Whaley, Kaitlin G. ^{[1
]}

Rosen, Michael J. ^{[1
,2
]}

机构：

[1] Cincinnati Childrens Hosp Med Ctr, Div Gastroenterol Hepatol & Nutr, 3333 Burnet Ave, Cincinnati, OH 45229 USA

[2] Univ Cincinnati, Coll Med, Dept Pediat, Cincinnati, OH USA

来源：

INFLAMMATORY BOWEL DISEASES | 2019年 / 25卷 / 01期

基金：

美国国家卫生研究院;

关键词：

acute severe ulcerative colitis; salvage therapy; infliximab; medical management; INFLAMMATORY-BOWEL-DISEASE; EVIDENCE-BASED CONSENSUS; RANDOMIZED CONTROLLED-TRIAL; DOUBLE-BLIND; INDUCTION THERAPY; INTRAVENOUS CYCLOSPORINE; VENOUS THROMBOEMBOLISM; HOSPITALIZED-PATIENTS; MAINTENANCE THERAPY; PRACTICE PARAMETERS;

D O I：

10.1093/ibd/izy208

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Acute severe ulcerative colitis is a medical emergency that requires prompt recognition, evaluation, and intervention. Patients require hospital admission with laboratory, radiographic, and endoscopic evaluation with initiation of corticosteroid treatment. Despite early intervention, many patients require salvage medical therapy, with some progressing to colectomy. Here we review important concepts and recent advances in the evaluation and medical management of adult and pediatric patients with acute severe ulcerative colitis.

引用

页码：56 / 66

页数：11

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