Indocyanine green enhanced transpupillary thermotherapy in combination with ophthalmic artery chemosurgery for retinoblastoma

被引：11
|
作者：
Francis, Jasmine H.
Abramson, David H. [1 ,2 ,3 ]
Brodie, Scott E. [4 ]
Marr, Brian P. [3 ]
机构：
[1] Mem Sloan Kettering Canc Ctr, Ophthalm Oncol Serv, Dept Ophthalm Oncol, New York, NY 10065 USA
[2] New York Presbyterian Hosp, Dept Ophthalmol, New York, NY USA
[3] Weill Cornell Med Ctr, Dept Ophthalmol, New York, NY USA
[4] Mt Sinai Sch Med, Dept Ophthalmol, New York, NY USA
来源：
BRITISH JOURNAL OF OPHTHALMOLOGY | 2013年 / 97卷 / 02期
关键词：
SUBFOVEAL CHOROIDAL NEOVASCULARIZATION; INTRAOCULAR RETINOBLASTOMA; INTRAARTERIAL CHEMOTHERAPY; MACULAR DEGENERATION; LASER TREATMENT; MELANOMA; CHEMOREDUCTION; ANGIOGRAPHY; MANAGEMENT;
D O I：
10.1136/bjophthalmol-2012-302495
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Purpose Review our experience in the use of indocyanine green (ICG) enhanced transpupillary thermotherapy (TTT) in combination with ophthalmic artery chemosurgery for retinoblastomas unresponsive to standard TTT. Methods Single centre, retrospective study of 16 eyes in 13 retinoblastoma patients treated with TTT and ICG via indirect ophthalmoscope: 23 treatments of 16 eyes, with a mean follow-up of 12.1 months (range 3-35 months). Outcome measures included tumour response and electroretinogram. Results Treatment resulted in significant tumour regression in all eyes: 13 eyes with well-differentiated characteristics, 2 with implanting vitreous seeds and 1 eye refractory to traditional TTT. ERG function was retained in all eyes. Conclusions ICG-enhanced TTT with ophthalmic artery chemosurgery can effectively treat retinoblastoma refractory to conventional focal treatments without deleterious ocular side effects.
引用
收藏
页码：164 / 168
页数：5
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