Detection of dental decay and its extent using ac impedance spectroscopy

被引:47
作者
Longbottom, C
Huysmans, MCDNJ
Pitts, NB
Los, P
Bruce, PG
机构
[1] UNIV NIJMEGEN,INST DENT CLIN RES,TRIKON,DEPT CARIOL & ENDODONTOL,NIJMEGEN,NETHERLANDS
[2] UNIV ST ANDREWS,SCH CHEM,ST ANDREWS KY16 9AJ,FIFE,SCOTLAND
关键词
D O I
10.1038/nm0296-235
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Dental caries (decay), the most prevalent of diseases, represents a health problem of immense proportions(1). It principally affects posterior (back) teeth on occlusal (biting) and approximal (adjacent contacting) surfaces. Caries starts as a subsurface demineralization of enamel, may progress to the underlying dentine and, eventually, to cavitation of the surface. Accurate diagnosis before cavitation would permit targeted preventive treatment, thereby significantly improving dental health and reducing the need for expensive drilling and filling. Inaccessibility of caries initiation sites and recent changes in lesion morphology contribute to the relatively poor accuracy of conventional diagnostic methods(2). Among alternative techniques, measurements of electrical resistance(3-5) have shown the most promise. Here we described new experimental technique that demonstrates an outstanding 100% correlation between a.c. impedance measurements of whole teeth and the actual extent of approximal caries in vitro. Only relatively minor modifications should be required to transfer the technique to in vivo applications.
引用
收藏
页码:235 / 237
页数:3
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