Dibenzothiophenesulfilimines: A Convenient Approach to Intermolecular Rhodium-Catalysed C-H Amidation

被引：18

作者：

Antoni, Patrick W. ^{[1
]}

Mackenroth, Alexandra V. ^{[1
]}

Mulks, Florian F. ^{[1
]}

Rudolph, Matthias ^{[1
]}

Helmchen, Guenter ^{[1
]}

Hashmi, A. Stephen K. ^{[1
,2
]}

机构：

[1] Heidelberg Univ, Inst Organ Chem, Neuenheimer Feld 270, D-69120 Heidelberg, Germany

[2] King Abdulaziz Univ, Fac Sci, Chem Dept, Jeddah 21589, Saudi Arabia

来源：

CHEMISTRY-A EUROPEAN JOURNAL | 2020年 / 26卷 / 37期

关键词：

amidation; C-H activation; homogeneous catalysis; rhodium; sulfilimines; transition-metal catalysis; BOND-FORMING REACTIONS; PHOTOCHEMISTRY; ANNULATION; ANTHRANILS; ACCESS;

D O I：

10.1002/chem.202002371

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A sulfilimine-based Group 9 transition-metal-catalysed C-H amidation procedure is reported. Dibenzothiophene-based sulfilimines were shown to constitute a class of novel amidation reagents which enable the transfer of a wide range of N-sulfonyl and N-acyl moieties. It was demonstrated that sulfilimines, which are easily accessible from cheap reagents, are safe-to-handle and represent broadly applicable amidation reagents. The dibenzothiophene can be recycled after use. The C-H amidation was shown to proceed with high selectivity and gave the mono-amidated products, mostly in good to excellent yields.

引用

页码：8235 / 8238

页数：4

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