Long-term survival in a child with a central nervous system medulloepithelioma

被引：16

作者：

Moftakhar, Parham ^{[1
]}

Fan, Xuemo ^{[2
,3
]}

Hurvitz, Carole H. ^{[4
]}

Black, Keith L. ^{[1
]}

Danielpour, Moise ^{[1
]}

机构：

[1] Cedars Sinai Med Ctr, Dept Neurosurg, Los Angeles, CA 90048 USA

[2] Cedars Sinai Med Ctr, Dept Pathol, Los Angeles, CA 90048 USA

[3] Cedars Sinai Med Ctr, Dept Lab Med, Los Angeles, CA 90048 USA

[4] Cedars Sinai Med Ctr, Div Pediat Hematol Oncol, Los Angeles, CA 90048 USA

来源：

JOURNAL OF NEUROSURGERY-PEDIATRICS | 2008年 / 2卷 / 05期

关键词：

chemotherapy; medulloepithelioma; radiation; stem cell;

D O I：

10.3171/PED.2008.2.11.349

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Central nervous system medulloepitheliomas are extremely rare and malignant (World Health Organization Grade IV) primitive neuroectodermal tumors (PNETs) that arise in childhood. Unlike other PNETs, medulloepitheliomas have a dismal prognosis, with only 2 reported cases in the literature in which the patient survived beyond 5 years after treatment. The authors report on the third known case of a child who survived longer than 5 years. A review of all the published cases of medulloepithelioma is also presented, and alternative treatment strategies for PNET tumors, including high-dose chemotherapy with stem-cell rescue, are discussed. (DOI: 10.3171/PED.2008.2.11.349)

引用

页码：339 / 345

页数：7

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