Bioinformatic methods to exploit mass spectrometric data for proteomic applications

被引：37

作者：

Chalkley, RJ ^{[1
]}

Hansen, KC

Baldwin, MA

机构：

[1] Univ Calif San Francisco, Dept Pharmaceut Chem, San Francisco, CA 94143 USA

[2] Univ Colorado, Sch Med, Hlth Sci Ctr, Aurora, CO USA

[3] Lawrence Livermore Natl Lab, Livermore, CA 94551 USA

来源：

BIOLOGICAL MASS SPECTROMETRY | 2005年 / 402卷

关键词：

D O I：

10.1016/S0076-6879(05)02009-4

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The new technologies in mass spectrometric analysis of peptides and proteins necessary to accommodate proteomics-scale analyses require, in turn, concomitant development of informatics technologies suitable for very large-scale data handling and analysis. This chapter focuses on the data analysis tools available to the community for analysis of mass spectrometric proteomics data. Different database searching strategies are discussed for peptide and protein identification, and approaches and tools available for comparative quantitative analysis of samples are outlined.

引用

页码：289 / 312

页数：24

共 65 条

[1] AMINO-ACID SUBSTITUTION MATRICES FROM AN INFORMATION THEORETIC PERSPECTIVE [J].

ALTSCHUL, SF .

JOURNAL OF MOLECULAR BIOLOGY, 1991, 219 (03) :555-565

[2] PROTEIN DATABASE SEARCHES FOR MULTIPLE ALIGNMENTS [J].

ALTSCHUL, SF ;

LIPMAN, DJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (14) :5509-5513

[3] Gapped BLAST and PSI-BLAST: a new generation of protein database search programs [J].

Altschul, SF ;

Madden, TL ;

Schaffer, AA ;

Zhang, JH ;

Zhang, Z ;

Miller, W ;

Lipman, DJ .

NUCLEIC ACIDS RESEARCH, 1997, 25 (17) :3389-3402

[4] Protein sequence databases [J].

Apweiler, R ;

Bairoch, A ;

Wu, CH .

CURRENT OPINION IN CHEMICAL BIOLOGY, 2004, 8 (01) :76-80

[5] An integrated approach to proteome analysis: Identification of proteins associated with cardiac hypertrophy [J].

Arnott, D ;

O'Connell, KL ;

King, KL ;

Stults, JT .

ANALYTICAL BIOCHEMISTRY, 1998, 258 (01) :1-18

[6]

BAKER PR, 2004, P 52 ANN C AM SOC MA

[7] GenBank [J].

Benson, DA ;

Karsch-Mizrachi, I ;

Lipman, DJ ;

Ostell, J ;

Wheeler, DL .

NUCLEIC ACIDS RESEARCH, 2005, 33 :D34-D38

[8]

Berndt P, 1999, ELECTROPHORESIS, V20, P3521, DOI 10.1002/(SICI)1522-2683(19991201)20:18<3521::AID-ELPS3521>3.0.CO

[9]

2-8

[10] NOMENCLATURE FOR PEPTIDE FRAGMENT IONS (POSITIVE-IONS) [J].

BIEMANN, K .

METHODS IN ENZYMOLOGY, 1990, 193 :886-887

← 1 2 3 4 5 6 7 →