Primary tracheal tumours

被引:282
作者
Macchiarini, P [1 ]
机构
[1] Univ Barcelona, Hosp Clin Barcelona, Dept Gen Thorac Surg, E-30889 Barcelona, Spain
关键词
D O I
10.1016/S1470-2045(05)70541-6
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Primary tumours of the trachea can be benign or malignant and account for fewer than 0.1% of tumours. However, they are a diagnostic and therapeutic challenge. Benign tumours are usually misdiagnosed as asthma or chronic lung disease, and can delay diagnosis for months or years. Because of their rapid growth and onset of haemoptysis, malignant tumours are often diagnosed earlier than benign tumours and patients thus often present with locally advanced disease. Inappropriate treatment is an equally frustrating issue. Modem techniques for tracheal surgery-laryngotracheal, tracheal, or carinal resection-combined with radiotherapy, can be offered curatively with low perioperative risks. Nevertheless, the low numbers of patients undergoing resection and the associated poor survival in epidemiological studies over the past two decades have shown that surgery is rarely considered outside referral centres, with radiotherapy or another form of local treatment (eg, endotracheal stents, debridement, brachytherapy) generally preferred. The liberal use of these other techniques should be avoided because surgery has the potential to cure all patients with benign and low-grade tumours and most patients with malignant primary tracheal tumours, and other techniques are usually palliative at best.
引用
收藏
页码:83 / 91
页数:9
相关论文
共 69 条
[1]   Adenoid cystic carcinoma of the trachea [J].
Azar, T ;
Abdul-Karim, FW ;
Tucker, HM .
LARYNGOSCOPE, 1998, 108 (09) :1297-1300
[2]  
BARKER E, IN PRESS CLIN EXP IM
[3]  
Beheshti J., 2004, SURG TRACHEA BRONCHI, P73
[4]  
Beheshti J, 2004, SURG TRACHEA BRONCHI, P86, DOI [10.1055/s-0039-1688903, DOI 10.1055/S-0039-1688903]
[5]   TRACHEAL TUMOURS [J].
BENNETTS, FE .
POSTGRADUATE MEDICAL JOURNAL, 1969, 45 (525) :446-&
[6]   Contemporary staging and prognosis for primary tracheal malignancies: A population-based analysis [J].
Bhattacharyya, N .
OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 2004, 131 (05) :639-642
[7]   Results of treating primary tumors of the trachea with radiotherapy [J].
Chao, MWT ;
Smith, JG ;
Laidlaw, C ;
Joon, DL ;
Ball, D .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1998, 41 (04) :779-785
[8]   RADIOTHERAPY FOR PRIMARY-CARCINOMA OF THE TRACHEA [J].
CHEUNG, AYC .
RADIOTHERAPY AND ONCOLOGY, 1989, 14 (04) :279-285
[9]  
Choi NC, 2004, SURG TRACHEA BRONCHI, P791
[10]   Low-dose spiral CT: Application to surface-rendered three-dimensional imaging of central airways [J].
Choi, YW ;
McAdams, HP ;
Jeon, SC ;
Park, CK ;
Lee, SJ ;
Kim, BS ;
Kim, JH ;
Hahm, CK .
JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 2002, 26 (03) :335-341