Star-shaped poly[2-(dimethylamino)ethyl methacrylate] and its derivatives: toward new properties and applications

被引:26
作者
Plamper, Felix A. [1 ]
Synatschke, Christopher V. [2 ]
Majewski, Alexander P. [2 ]
Schmalz, Alexander [2 ]
Schmalz, Holger [2 ]
Mueller, Axel H. E. [2 ,3 ]
机构
[1] Rhein Westfal TH Aachen, Inst Phys Chem, D-52056 Aachen, Germany
[2] Univ Bayreuth, D-95440 Bayreuth, Germany
[3] Johannes Gutenberg Univ Mainz, Inst Organ Chem, D-55099 Mainz, Germany
关键词
stimuli-responsive polymer; star-shaped polymer; micellization; gene transfection; hydrogel; hybrids; TRANSFER RADICAL POLYMERIZATION; NONVIRAL GENE DELIVERY; BLOCK-COPOLYMERS; POLY(N; N-DIMETHYLAMINOETHYL METHACRYLATE); AMPHIPHILIC STAR; 2-(DIMETHYLAMINO)ETHYL METHACRYLATE; TRANSFECTION EFFICIENCY; MAGNETIC NANOPARTICLES; WEAK POLYELECTROLYTES; RAFT POLYMERIZATION;
D O I
10.14314/polimery.2014.066
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
The versatility of polymer and hybrid systems containing the polycation PDMAEMA, especially in the star-shaped topology, is reviewed. Different complexation schemes are addressed, including the use of stimuli-responsive counterions. This leads to the use of PDMAEMA stars for nucleotide transfection or advanced hydrogel formulations.
引用
收藏
页码:66 / 73
页数:8
相关论文
共 105 条
[1]   Stimuli responsive polymers for biomedical applications [J].
Alarcón, CDH ;
Pennadam, S ;
Alexander, C .
CHEMICAL SOCIETY REVIEWS, 2005, 34 (03) :276-285
[2]   Cationic Amphiphilic Star and Linear Block Copolymers: Synthesis, Self-Assembly, and in Vitro Gene Transfection [J].
Alhoranta, Anu M. ;
Lehtinen, Julia K. ;
Urtti, Arto O. ;
Butcher, Sarah J. ;
Aseyev, Vladimir O. ;
Tenhu, Heikki J. .
BIOMACROMOLECULES, 2011, 12 (09) :3213-3222
[3]   Amphiphilic star homo- and block copolymers of 2-(dimethylamino) ethyl-methacrylate via atom transfer radical polymerization [J].
Amin, A. .
JOURNAL OF MACROMOLECULAR SCIENCE PART A-PURE AND APPLIED CHEMISTRY, 2007, 44 (03) :329-335
[4]  
Armes SP, 2003, SELF-ASSEMBLY, P260
[5]   Switching the inside and the outside of aggregates of water-soluble block copolymers with double thermoresponsivity [J].
Arotçaréna, M ;
Heise, B ;
Ishaya, S ;
Laschewsky, A .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (14) :3787-3793
[6]   Non-ionic Thermoresponsive Polymers in Water [J].
Aseyev, Vladimir ;
Tenhu, Heikki ;
Winnik, Francoise M. .
SELF ORGANIZED NANOSTRUCTURES OF AMPHIPHILIC BLOCK COPOLYMERS II, 2011, 242 :29-89
[7]   UCST wetting transitions of polyzwitterionic brushes driven by self-association [J].
Azzaroni, O ;
Brown, AA ;
Huck, WTS .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 45 (11) :1770-1774
[8]   Micellar Interpolyelectrolyte Complexes Formed by Star-Shaped Poly(acrylic acid) with Double Hydrophilic Cationic Diblock Copolymer [J].
Babin, I. A. ;
Pergushov, D. V. ;
Wolf, A. ;
Plamper, F. A. ;
Schmalz, H. ;
Mueller, A. H. E. ;
Zezin, A. B. .
DOKLADY PHYSICAL CHEMISTRY, 2011, 441 :219-223
[9]   Synthesis of star polymers using RAFT polymerization: What is possible? [J].
Barner-Kowollik, Christopher ;
Davis, Thomas P. ;
Stenzel, Martina H. .
AUSTRALIAN JOURNAL OF CHEMISTRY, 2006, 59 (10) :719-727
[10]   Core cross-linked star polymers via controlled radical polymerisation [J].
Blencowe, Anton ;
Tan, Jing Fung ;
Goh, Tor Kit ;
Qiao, Greg G. .
POLYMER, 2009, 50 (01) :5-32