A novel glucose biosensor platform based on Ag@AuNPs modified graphene oxide nanocomposite and SERS application

被引:120
作者
Gupta, Vinod Kumar [1 ,2 ]
Atar, Necip [3 ]
Yola, Mehmet Lutfi [4 ,5 ]
Eryilmaz, Merve [6 ]
Torul, Hilal [6 ]
Tamer, Ugur [6 ]
Boyaci, Ismail Hakki [7 ]
Ustundag, Zafer [3 ]
机构
[1] Indian Inst Technol, Dept Chem, Roorkee 247667, Uttar Pradesh, India
[2] Dr RML Avadh Univ, Faizabad 224001, Uttar Pradesh, India
[3] Dumlupinar Univ, Fac Arts & Sci, Dept Chem, Kutahya, Turkey
[4] Sinop Univ, Fac Arts & Sci, Dept Chem, Sinop, Turkey
[5] Hacettepe Univ, Fac Pharm, Dept Analyt Chem, TR-06100 Ankara, Turkey
[6] Gazi Univ, Fac Pharm, Dept Analyt Chem, Ankara, Turkey
[7] Hacettepe Univ, Fac Engn, Dept Food Engn, Ankara, Turkey
关键词
Graphene oxide; Ag@AuNPs; Characterization; Glucose biosensor; SERS; ENHANCED RAMAN-SCATTERING; GOLD NANOPARTICLES; PVC MATRIX; POTENTIOMETRIC SENSOR; OPTICAL-PROPERTIES; ELECTRODE; ACID; SPECTROSCOPY; MEMBRANE; FABRICATION;
D O I
10.1016/j.jcis.2013.06.007
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
This study represents a novel template demonstration of a glucose biosensor based on mercaptophenyl boronic acid (MBA) terminated Ag@AuNPs/graphene oxide (Ag@AuNPs-GO) nanomaterials. The nanocomposites were characterized by transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), and X-ray diffraction (XRD) method. The TEM image shows that Ag@AuNPs in the nanocomposite is in the range of diameters of 10-20 nm. The nanocomposite was used for the determination of glucose through the complexation between boronic acid and diol groups of glucose. Thus, a novel glucose biosensor was further fabricated by immobilizing glucose oxidase (GOD) into MBA terminated Ag@AuNPs-GO nanocomposite film (MBA-Ag@AuNPs-GO). The linearity range of glucose was obtained as 2-6 mM with detection limit of 0.33 mM. The developed biosensor was also applied successfully for the determination of glucose in blood samples. The concentration value of glucose in blood samples was calculated to be 1.97 +/- 0.002 mM from measurements repeated for six times. (C) 2013 Elsevier Inc. All rights reserved.
引用
收藏
页码:231 / 237
页数:7
相关论文
共 75 条
[61]   Preparation and optical properties of colloidal silver nanoparticles at a high Ag+ concentration [J].
Ullah, MH ;
Il, K ;
Ha, CS .
MATERIALS LETTERS, 2006, 60 (12) :1496-1501
[62]   A decade of Raman spectroscopy in art and archaeology [J].
Vandenabeele, Peter ;
Edwards, Howell G. M. ;
Moens, Luc .
CHEMICAL REVIEWS, 2007, 107 (03) :675-686
[63]   Fabrication of Graphene-Polymer Nanocomposites With Higher-Order Three-Dimensional Architectures [J].
Vickery, Jemma L. ;
Patil, Avinash J. ;
Mann, Stephen .
ADVANCED MATERIALS, 2009, 21 (21) :2180-+
[64]   Amperometric glucose biosensor based on multilayer films via layer-by-layer self-assembly of multi-wall carbon nanotubes, gold nanoparticles and glucose oxidase on the Pt electrode [J].
Wu, Bao-Yan ;
Hou, Shi-Hua ;
Yin, Feng ;
Zhao, Zi-Xia ;
Wang, Yan-Yan ;
Wang, Xin-Sheng ;
Chen, Qiang .
BIOSENSORS & BIOELECTRONICS, 2007, 22 (12) :2854-2860
[65]   Multifunctional Hybrid Nanogel for Integration of Optical Glucose Sensing and Self-Regulated Insulin Release at Physiological pH [J].
Wu, Weitai ;
Mitra, Nivedita ;
Yan, Elsa C. Y. ;
Zhou, Shuiqin .
ACS NANO, 2010, 4 (08) :4831-4839
[66]   Graphene-Based Photocatalysts for Hydrogen Generation [J].
Xiang, Quanjun ;
Yu, Jiaguo .
JOURNAL OF PHYSICAL CHEMISTRY LETTERS, 2013, 4 (05) :753-759
[67]   Synergetic Effect of MoS2 and Graphene as Cocatalysts for Enhanced Photocatalytic H2 Production Activity of TiO2 Nanoparticles [J].
Xiang, Quanjun ;
Yu, Jiaguo ;
Jaroniec, Mietek .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2012, 134 (15) :6575-6578
[68]   Graphene-based semiconductor photocatalysts [J].
Xiang, Quanjun ;
Yu, Jiaguo ;
Jaroniec, Mietek .
CHEMICAL SOCIETY REVIEWS, 2012, 41 (02) :782-796
[69]   Preparation and electrochemical characterization of nitrogen doped graphene by microwave as supporting materials for fuel cell catalysts [J].
Xin, Yuchen ;
Liu, Jian-guo ;
Jie, Xiao ;
Liu, Wenming ;
Liu, Fuqiang ;
Yin, Ying ;
Gu, Jun ;
Zou, Zhigang .
ELECTROCHIMICA ACTA, 2012, 60 :354-358
[70]   Graphene-Metal Particle Nanocomposites [J].
Xu, Chao ;
Wang, Xin ;
Zhu, Junwu .
JOURNAL OF PHYSICAL CHEMISTRY C, 2008, 112 (50) :19841-19845