Synthesis of Dienyl Ketones via Palladium(II)-Catalyzed Direct Cross-Coupling Reactions between Simple Alkenes and Vinyl Ketones: Application to the Synthesis of Vitamin A1 and Bornelone

被引：19
|
作者：
Zhang, Xiang [1 ,2 ]
Wang, Min [1 ,2 ]
Zhang, Ming-Xin [1 ,2 ]
Xu, Yun-He [1 ,2 ]
Loh, Teck-Peng [1 ,2 ,3 ]
机构：
[1] Univ Sci & Technol China, Hefei Natl Lab Phys Sci Microscale, Hefei 230026, Anhui, Peoples R China
[2] Univ Sci & Technol China, Dept Chem, Hefei 230026, Anhui, Peoples R China
[3] Nanyang Technol Univ, Div Chem & Biol Chem, Sch Phys & Math Sci, Singapore 637371, Singapore
来源：
ORGANIC LETTERS | 2013年 / 15卷 / 21期
基金：
美国国家科学基金会; 中国博士后科学基金;
关键词：
C-H BONDS; STEREOCONTROLLED SYNTHESIS; STEREOSPECIFIC SYNTHESIS; OLEFINATION REACTION; EFFICIENT SYNTHESIS; SELECTIVE ACCESS; MONOTERPENES; ACRYLATES; ESTERS; ACID;
D O I：
10.1021/ol402692t
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient and general method for the synthesis of conjugated dienyl ketones via palladium(II) acetate catalyzed direct cross-coupling between simple alkenes and vinyl ketones is reported. This method has been successfully applied for the synthesis of Vitamin A1 and bornelone.
引用
收藏
页码：5531 / 5533
页数：3
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