Aggressive Coronary Artery Vasculopathy after Combined Heart-Lung Transplantation

被引:0
作者
Hayes, Don, Jr. [1 ,2 ]
Baker, Peter B. [1 ,2 ]
Astor, Todd L. [3 ]
Preston, Thomas J. [2 ]
Kirkby, Stephen [1 ,2 ]
Galantowicz, Mark [1 ,2 ]
Hoffman, Timothy M. [1 ,2 ]
机构
[1] Nationwide Childrens Hosp, Columbus, OH USA
[2] Ohio State Univ, Coll Med, Columbus, OH 43210 USA
[3] Massachusetts Gen Hosp, Boston, MA 02114 USA
关键词
Allograft Rejection; Bronchiolitis Obliterans Syndrome; Combined Heart and Lung Transplantation; Coronary Artery Vasculopathy;
D O I
10.1111/j.1747-0803.2012.00681.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Combined heart-lung transplantation remains as a treatment option for patients with cardiopulmonary failure. There is speculation that lung grafts protect the heart from developing graft vasculopathy after combined heart-lung transplantation. This protective mechanism is more likely, at best, a delay in the onset of coronary artery vasculopathy. We present our experiences in two cases of an aggressive form of cardiac allograft vasculopathy after combined heart-lung transplantation that resulted in the death of both patients.
引用
收藏
页码:E88 / E91
页数:4
相关论文
共 5 条
[1]  
Christie J.D., Edwards L.B., Kucheryavaya A.Y., Et al., The Registry of the International Society for Heart and Lung Transplantation: twenty-seventh official adult lung and heart-lung transplant report-2010, J Heart Lung Transplant, 29, pp. 1104-1118, (2010)
[2]  
Stehlik J., Edwards L.B., Kucheryavaya A.Y., Et al., The Registry of the International Society for Heart and Lung Transplantation: twenty-seventh official adult heart transplant report-2010, J Heart Lung Transplant, 29, pp. 1089-1103, (2010)
[3]  
Moffatt-Bruce S.D., Karamichalis J., Robbins R.C., Whyte R.I., Theodore J., Reitz B.A., Are heart-lung transplant recipients protected from developing bronchiolitis obliterans syndrome?, Ann Thorac Surg, 81, pp. 286-291, (2006)
[4]  
Deuse T., Sista R., Weill D., Et al., Review of heart-lung transplantation at Stanford, Ann Thorac Surg, 90, pp. 329-337, (2010)
[5]  
Vamvakopoulos J.E., Taylor C.J., Green C., Et al., Interleukin 1 and chronic rejection: possible genetic links in human heart allografts, Am J Transplant, 2, pp. 76-83, (2002)