Experiments were conducted to evaluate the effect of application rate, growth stage, and tank mixing azimsulfuron, bentazon, MCPA, propanil, or cyhalofop on the efficacy of bispyribac-sodium against early watergrass and late watergrass from rice fields in northern Greece. Mixtures of bispyribac-sodium with the insecticides carbaryl, diazinon, and dichlorvos were also evaluated. Bispyribac-sodium (24 to 36 g ai/ha) applied alone at the three- to four-leaf growth stage provided 89 to 100% control of earl), watergrass and 84 to 100% control of late watergrass. When bispyribac-sodium was applied alone at the five- to six-leaf growth stage of early watergrass and late warergrass, control ranged from 78 to 100% and 71 to 100%, respectively. Mixtures of bispyribac-sodium with azimsulfuron provided better control of both species at any growth stage than bispyribac-sodium applied alone. On the contrary, mixtures of bispyribac-sodium with bentazon, MCPA, or propanil were less effective on both species at any growth stage than bispyribac-sodium applied alone. A slight efficacy reduction occurred on both species for the mixture of bispyribac-sodium with cyhalofop. Mixtures of bispyribac-sodium with the insecticides carbaryl or dichlorvos showed reduced efficacy on both species, whereas increased efficacy on both species was observed for mixtures of bispyribac-sodium with diazinon as compared with the single application of bispyribac-sodium.