Chloroma of Pancreas-Initial Manifestation of a Secondary Leukemia after Stem Cell Transplantation Case Report and Review of the Literature

Chloroma is an extramedullary solid tumor consisting of immature myeloid cells. We report a patient with painless jaundice 6 years after allogeneic peripheral stem cell transplantation because of an acute myeloid leukemia leading us to the diagnosis of a chloroma of the pancreas as the first manifestation of a secondary host leukemia. A histological examination of unclear pancreatic tumors should be mandatory in patients with a history of leukemia. If surgical therapy is unavoidable because of stenosis symptoms or for histological proof, a resection should be avoided. Bypass surgery can ease the symptoms and it allows timely curative chemotherapy or stem cell transplantation.