The complex link between severity of asthma and rhinitis in mite allergic patients

被引：11

作者：

Antonicelli, Leonardo ^{[1
]}

Braschi, Maria Chiara ^{[1
]}

Bresciani, Megon ^{[2
]}

Bonifazi, Martina ^{[1
]}

Baldacci, Sandra ^{[2
]}

Angino, Anna ^{[2
]}

Pala, Anna Paola ^{[2
]}

Viegi, Giovanni ^{[3
]}

机构：

[1] Azienda Osped Univ Osped Riuniti, Allergy Unit, Dept Immunoallerg & Resp Dis, Ancona, Italy

[2] CNR, Inst Clin Physiol, Pulm Environm Epidemiol Unit, I-56100 Pisa, Italy

[3] CNR, Inst Biomed & Mol Immunol, Palermo, Italy

来源：

RESPIRATORY MEDICINE | 2013年 / 107卷 / 01期

关键词：

Asthma; Comorbidity; Mite hypersensitivity; Rhinitis; Severity; EXHALED NITRIC-OXIDE; RHINOSINUSITIS; CLASSIFICATION; ASSOCIATION; COEXISTENCE; PREVALENCE; SYMPTOMS; AIRWAYS; ONSET;

D O I：

10.1016/j.rmed.2012.09.023

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Aim: The aim of the study was to evaluate the link between the severity of upper and lower airways diseases in mite allergic patients with respiratory allergy. Patients and method: A multicentre, observational, cross-sectional study was carried out in 556 consecutively enrolled mite allergic patients with rhinitis and asthma comorbidity attending a specialist unit. Severity assessment of rhinitis and asthma was evaluated in accordance with ARIA and GINA guidelines. Results: Reliable data were available for 518 patients. The distribution of rhinitis severity was: 15.6% mild intermittent rhinitis, 4.4% moderate-severe intermittent rhinitis, 30.3% mild persistent rhinitis and 49.6% moderate persistent rhinitis. The distribution of asthma severity was: 41.3% mild intermittent asthma, 14.3% mild persistent asthma, 19.1% moderate persistent asthma and 25.3% severe persistent asthma. In patients with moderate-severe persistent rhinitis (49.5%) a significant trend (p = 0.005) was found pointing to an increased link with asthma severity. Conclusion: A link between respective severities of rhinitis and asthma was found in only half of mite allergic patients with rhinitis and asthma. (c) 2012 Elsevier Ltd. All rights reserved.

引用

页码：23 / 29

页数：7

共 30 条

[1] [Anonymous], 1997, NIH PUBL
[2] Allergic rhinitis and asthma comorbidity:: ARIA classification of rhinitis does not correlate with the prevalence of asthma
Antonicelli, L.
Micucci, C.
Voltolini, S.
Feliziani, V.
Senna, G. E.
Di Blasi, P.
Visona, G.
De Marco, R.
Bonifazi, F.
[J]. CLINICAL AND EXPERIMENTAL ALLERGY, 2007, 37 (06) : 954 - 960
[3] Asthma severity and medical resource utilisation
Antonicelli, L
Bucca, C
Neri, M
De Benedetto, F
Sabbatani, P
Bonifazi, F
Eichler, HG
Zhang, Q
Yin, DD
[J]. EUROPEAN RESPIRATORY JOURNAL, 2004, 23 (05) : 723 - 729
[4] Bjerg A., 2011, PLoS One, V17, P6, DOI DOI 10.1371/J0URNAL.P0NE.0016082
[5] Characteristics of intermittent and persistent allergic rhinitis:: DREAMS study group
Bousquet, J
Annesi-Maesano, I
Carat, F
Léger, D
Rugina, M
Pribil, C
El Hasnaoui, A
Chanal, I
[J]. CLINICAL AND EXPERIMENTAL ALLERGY, 2005, 35 (06) : 728 - 732
[6] Characteristics of patients with seasonal allergic rhinitis and concomitant asthma
Bousquet, J
Boushey, HA
Busse, WW
Canonica, GW
Durham, SR
Irvin, CG
Karpel, JP
van Cauwenberge, P
Chen, R
Iezzoni, DG
Harris, AG
[J]. CLINICAL AND EXPERIMENTAL ALLERGY, 2004, 34 (06) : 897 - 903
[7] Links between rhinitis and asthma
Bousquet, J
Vignola, AM
Demoly, P
[J]. ALLERGY, 2003, 58 (08) : 691 - 706
[8] Braunstahl Gert-Jan, 2009, Proc Am Thorac Soc, V6, P652, DOI 10.1513/pats.200906-052DP
[9] Rhinosinusitis in severe asthma
Bresciani, M
Paradis, L
Des Roches, A
Vernhet, H
Vachier, I
Godard, P
Bousquet, J
Chanez, P
[J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2001, 107 (01) : 73 - 80
[10] Common characteristics of upper and lower airways in rhinitis and asthma:: ARIA update, in collaboration with GA2LEN
Cruz, A. A.
Popov, T.
Pawankar, R.
Annesi-Maesano, I.
Fokkens, W.
Kemp, J.
Ohta, K.
Price, D.
Bousquet, J.
[J]. ALLERGY, 2007, 62 : 1 - 41

← 1 2 3 →