Chronic Pruritus

被引:284
作者
Yosipovitch, Gil [1 ,2 ,3 ]
Bernhard, Jeffrey D. [4 ]
机构
[1] Wake Forest Univ, Baptist Med Ctr, Dept Dermatol, Winston Salem, NC 27157 USA
[2] Wake Forest Univ, Baptist Med Ctr, Dept Neurobiol, Winston Salem, NC 27157 USA
[3] Wake Forest Univ, Baptist Med Ctr, Dept Anat, Winston Salem, NC 27157 USA
[4] Univ Massachusetts, Sch Med, Worcester, MA USA
关键词
UREMIC PRURITUS; DOUBLE-BLIND; HEMODIALYSIS-PATIENTS; ATOPIC-DERMATITIS; TOPICAL CORTICOSTEROIDS; CONTROLLED-TRIAL; NOCTURNAL ITCH; MIRTAZAPINE; GABAPENTIN; CROSSOVER;
D O I
10.1056/NEJMcp1208814
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
An otherwise healthy 55-year-old man reports that he has been itchy all over for 6 months. The itch interferes with falling asleep and wakes him repeatedly during the night. Initially, there was no rash, but during the past 4 months, itchy nodules and plaques have developed on his back, arms, and legs. Treatment with sedating and nonsedating oral antihistamines and topical glucocorticoids has had no effect. How would you evaluate and manage this case?
引用
收藏
页码:1625 / 1634
页数:10
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