Laser-scanning photoacoustic microscopy with ultrasonic phased array transducer

被引：16

作者：

Zheng, Fan ^{[1
]}

Zhang, Xiangyang ^{[2
]}

Chiu, Chi Tat ^{[1
]}

Zhou, Bill L. ^{[2
]}

Shung, K. Kirk ^{[1
]}

Zhang, Hao F. ^{[3
]}

Jiao, Shuliang ^{[2
]}

机构：

[1] Univ So Calif, Dept Biomed Engn, Los Angeles, CA 90089 USA

[2] Univ So Calif, Keck Sch Med, Dept Ophthalmol, Los Angeles, CA 90033 USA

[3] Northwestern Univ, Dept Biomed Engn, Evanston, IL 60208 USA

来源：

BIOMEDICAL OPTICS EXPRESS | 2012年 / 3卷 / 11期

基金：

美国国家卫生研究院;

关键词：

IN-VIVO; RESOLUTION;

D O I：

10.1364/BOE.3.002694

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

In this paper, we report our latest progress on proving the concept that ultrasonic phased array can improve the detection sensitivity and field of view (FOV) in laser-scanning photoacoustic microscopy (LS-PAM). A LS-PAM system with a one-dimensional (1D) ultrasonic phased array was built for the experiments. The 1D phased array transducer consists of 64 active elements with an overall active dimension of 3.2 mm x 2 mm. The system was tested on imaging phantom and mouse ear in vivo. Experiments showed a 15 dB increase of the signal-to-noise ratio (SNR) when beamforming was employed compared to the images acquired with each single element. The experimental results demonstrated that ultrasonic phased array can be a better candidate for LS-PAM in high sensitivity applications like ophthalmic imaging. (C) 2012 Optical Society of America

引用

页码：2694 / 2699

页数：6

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