The Allergic Rhinitis and Its Impact on Asthma (ARIA) Approach of Value-Added Medicines: As-Needed Treatment in Allergic Rhinitis

被引：24

作者：

Bousquet, Jean ^{[1
,2
,3
,4
,5
]}

Toumi, Mondher ^{[6
]}

Sousa-Pinto, Bernardo ^{[7
,8
,9
]}

Anto, Josep M. ^{[10
,11
,12
,13
]}

Bedbrook, Anna ^{[14
]}

Czarlewski, Wienczyslawa ^{[15
]}

Valiulis, Arunas ^{[16
]}

Ansotegui, Ignacio J. ^{[17
]}

Bosnic-Anticevich, Sinthia ^{[18
]}

Brussino, Luisa ^{[19
]}

Canonica, Walter ^{[20
]}

Cecchi, Lorenzo ^{[21
]}

Cherrez-Ojeda, Ivan ^{[22
]}

Chivato, Tomas ^{[23
]}

Costa, Elisio M. ^{[24
]}

Cruz, Alvaro A. ^{[25
]}

Del Giacco, Stefano ^{[26
]}

Fonseca, Joao A. ^{[7
,8
,9
]}

Gemicioglu, Bilun ^{[27
]}

Haahtela, Tari ^{[28
]}

Ivancevich, Juan Carlos ^{[29
]}

Jutel, Marek ^{[30
,31
]}

Kaidashev, Igor ^{[32
]}

Klimek, Ludger ^{[33
,34
]}

Kvedariene, Violeta ^{[35
,36
]}

Kuna, Piotr ^{[37
]}

Larenas-Linnemann, Desiree E. ^{[38
]}

Lipworth, Brian ^{[39
]}

Morais-Almeida, Mario ^{[40
]}

Mullol, JoaQuim ^{[41
]}

Papadopoulos, Nikolaos G. ^{[42
]}

Patella, Vincenzo ^{[43
]}

Pham-Thi, Nham ^{[44
]}

Regateiro, Frederico S. ^{[45
,46
,47
]}

Rouadi, Philip W. ^{[48
,49
]}

Samolinski, Boleslaw ^{[50
]}

Sheikh, Aziz ^{[51
]}

Taborda-Barata, Luis ^{[52
,53
,54
]}

Ventura, Maria Teresa ^{[55
]}

Yorgancioglu, Arzu ^{[56
]}

Zidarn, Mihaela ^{[57
,58
]}

Zuberbier, Torsten ^{[1
,2
,3
,5
]}

机构：

[1] Charite Univ Med Berlin, Inst Allergol, Berlin, Germany

[2] Free Univ Berlin, Berlin, Germany

[3] Humboldt Univ, Berlin, Germany

[4] Univ Hosp Montpellier, Montpellier, France

[5] Fraunhofer Inst Translat Med & Pharmacol ITMP, Allergol & Immunol, Berlin, Germany

[6] Aix Marseille Univ, Publ Hlth, Marseille, France

[7] Univ Porto, Dept Community Med, MEDCIDS, Fac Med, Porto, Portugal

[8] Univ Porto, Ctr Hlth Technol, Serv Res, CINTESIS, Porto, Portugal

[9] Univ Porto, RISE, Hlth Res Network, Porto, Portugal

[10] Barcelona Inst Global Hlth, ISGlobaL, Barcelona, Spain

[11] Hosp Mar, Med Res Inst, Barcelona, Spain

[12] Univ Pompeu Fabra, Barcelona, Spain

[13] CIBER Epidemiol & Salud Publ, Barcelona, Spain

[14] ARIA, Montpellier, France

[15] Med Consulting Czarlewski, Levallois Perret, France

[16] Vilnius Univ, Inst Clin Med, Inst Hlth Sci, Med Fac, Vilnius, Lithuania

[17] Hosp Quironsalud Bizkaia, Dept Allergy & Immunol, Bilbao, Spain

[18] Univ Sydney, Woolcock Inst Med Res, Qual Use Resp Med Grp, Sydney, NSW, Australia

[19] Univ Torino, Mauriziano Hosp, Dept Med Sci, Allergy & Clin Immunol Unit, Turin, Italy

[20] Humanitas Univ, Humanitas Clin & Res Ctr IRCCS, Dept Biomed Sci, Pieve Emanuele & Personalized Med Asthma & Allerg, Rozzano, Italy

[21] USL Toscana Ctr, SOS Allergol & Clin Immunol, Prato, Italy

[22] Espiritu Santo Univ, Dept Allergy & Pulmonol, Samborondon, Ecuador

[23] Univ CEU San Pablo, Sch Med, Madrid, Spain

[24] Univ Porto Porto4Ageing, Fac Pharm, Competence Ctr Act & Hlth Ageing, UCIBIO, Porto, Portugal

[25] Univ Fed Bahia, Fundacao ProAR, GARD, WHO Planning Grp, Salvador, BA, Brazil

[26] Univ Cagliari, Univ Hosp Duilio Casula, Dept Med Sci & Publ Hlth, Unit Allergy & Clin Immunol, Cagliari, Italy

[27] Istanbul Univ Cerrahpasa, Cerrahpasa Fac Med, Dept Pulm Dis, Istanbul, Turkey

[28] Univ Helsinki, Helsinki Univ Hosp, Skin & Allergy Hosp, Helsinki, Finland

[29] Clin Santa Isabel, Serv Alergia Immunol, Buenos Aires, Argentina

[30] Wroclaw Med Univ, Dept Clin Immunol, Wroclaw, Poland

[31] ALL MED Med Res Inst, Wroclaw, Poland

[32] Poltava State Med Univ, Poltava, Poltava Oblast, Ukraine

[33] Univ Med Mainz, Dept Otolaryngol Head & Neck Surg, Mainz, Germany

[34] Ctr Rhinol & Allergol, Wiesbaden, Germany

[35] Vilnius Univ, Inst Biomed Sci, Fac Med, Dept Pathol, Vilnius, Lithuania

[36] Vilnius Univ, Inst Clin Med, Fac Med, Clin Chest Dis & Allergol, Vilnius, Lithuania

[37] Med Univ Lodz, Barlicki Univ Hosp, Div Internal Med Asthma & Allergy, Lodz, Poland

[38] Med Sur Clin Fdn & Hosp, Ctr Excellence Asthma & Allergy, Mexico City, Mexico

[39] Univ Dundee, Ninewells Hosp, Med Res Inst, Scottish Ctr Resp Res, Dundee, Angus, Scotland

[40] CUF Descobertas Hosp, Allergy Ctr, Lisbon, Portugal

[41] Univ Barcelona, Hosp Clin, ENT Dept, Smell Clin, Barcelona, Spain

[42] Univ Athens, Allergy Dept, Pediat Clin 2, Athens, Greece

[43] St Maria Speranza Hosp, Dept Med, Div Allergy & Clin Immunol, Agcy Hlth ASL Salerno, Battipaglia, Salerno, Italy

[44] Ecole Polytech Palaiseau, Inst Rech Biomed Armees, Bretigny Sur Orge, France

[45] Ctr Hosp & Univ Coimbra, Allergy & Clin Immunol Unit, Coimbra, Portugal

[46] Univ Coimbra, Inst Immunol, Fac Med, Coimbra, Portugal

[47] Univ Coimbra, Coimbra Inst Clin & Biomed Res, Fac Med, ICBR, Coimbra, Portugal

[48] Eye & Ear Univ Hosp, Dept Otolaryngol Head & Neck Surg, Beirut, Lebanon

[49] Dar Al Shifa Hosp, ENT Dept, Salmiya, Kuwait

[50] Med Univ Warsaw, Dept Prevent Environm Hazards Allergol & Immunol, Warsaw, Poland

来源：

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE | 2022年 / 10卷 / 11期

关键词：

Value-added medicine; Repurposing; Allergic rhinitis; MASK-air; Treatment; PERSON-CENTERED CARE; QUALITY-OF-LIFE; NASAL SPRAY; MOBILE TECHNOLOGY; WORK PRODUCTIVITY; MANAGEMENT; GUIDELINE; QUESTIONNAIRE; VALIDATION; MULTIMORBIDITY;

D O I：

10.1016/j.jaip.2022.07.020

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Drug repurposing is a major field of value-added medicine. It involves investigating and evaluating existing drugs for new therapeutic purposes that address unmet healthcare needs. Several unmet needs in allergic rhinitis could be improved by drug repurposing. This could be game-changing for disease management. Current medications for allergic rhinitis are centered on continuous long-term treatment, and medication registration is based on randomized controlled trials carried out for a minimum of 14 days with adherence of 70% or greater. A new way of treating allergic rhinitis is to propose as-needed treatment depending on symptoms, rather than classical continuous treatment. This rostrum will discuss existing clinical trials on as-needed treatment for allergic rhinitis and real-world data obtained by the mobile health app MASK-air, which fo-cuses on digitally-enabled, patient-centered care pathways. (c) 2022 American Academy of Allergy, Asthma & Immunology (J Allergy Clin Immunol Pract 2022;10:2878-88)

引用

页码：2878 / 2888

页数：11

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