Effects of circuit miniaturization in reducing inflammatory response to infant cardiopulmonary bypass by elimination of allogeneic blood products

被引：59

作者：

Hickey, Edward

Karamlou, Tara

You, Jamie

Ungerleider, Ross M.

机构：

[1] Oregon Hlth & Sci Univ, Div Pediat Cardiac Surg, Portland, OR 97201 USA

[2] Hosp Sick Children, Div Cardiovasc Surg, Toronto, ON M5G 1X8, Canada

来源：

ANNALS OF THORACIC SURGERY | 2006年 / 81卷 / 06期

关键词：

D O I：

10.1016/j.athoracsur.2006.02.071

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Conventional neonatal cardiopulmonary bypass requires the use of large volumes of allogeneic blood to prevent unacceptable hemodilution. Evidence is accumulating to suggest that the use of blood products during cardiopulmonary bypass has a negative effect on clinical recovery through inflammatory side effects. This would suggest an advantage for eliminating blood use in infant cardiopulmonary bypass through circuit miniaturization. In this article, we review the data supporting this rationale and provide the results from studies in our laboratory that emphasize the benefits of circuit miniaturization.

引用

页码：S2367 / S2372

页数：6

共 75 条

[1] Levels of inflammatory markers in the blood processed by autotransfusion devices during cardiac surgery associated with cardiopulmonary bypass circuit [J].