Understanding the role of the microenvironment during definitive hemopoietic development

被引:23
作者
Cao, Huimin [1 ,2 ]
Oteiza, Ana [1 ,3 ]
Nilsson, Susan K. [1 ,2 ]
机构
[1] CSIRO, CSIRO Mat Sci & Engn, Clayton, Vic 3169, Australia
[2] Univ Melbourne, Dept Pathol, Melbourne, Vic 3010, Australia
[3] Univ Tromso, Fac Hlth Sci, Dept Med Biol, Vasc Biol Res Grp, Tromso, Norway
关键词
STEM-CELL-NICHE; GONAD-MESONEPHROS REGION; MARROW STROMAL CELLS; BONE-MARROW; PROGENITOR CELLS; CHEMOKINE SDF-1; YOLK-SAC; IN-VIVO; B-LYMPHOPOIESIS; GENE-EXPRESSION;
D O I
10.1016/j.exphem.2013.06.005
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Hemopoietic stem cells (HSCs) are sustained in a specific microenvironment known as the stem cell niche. Recent studies in adult bone marrow have identified osteoblasts and endothelial cells as two important supportive cell types within the niche and demonstrated that interactions between HSCs and cellular and extracellular components within the endosteal and perivascular regions are critical for HSC regulation. However, the understanding of the role of the microenvironment in definitive HSC establishment, expansion, and maintenance during embryonic development is extremely limited. This review focuses on what is known about the components of each HSC microenvironment at various developmental stages and their known functional roles. Crown Copyright (C) 2013 Published by Elsevier Inc. on behalf of ISEH - Society for Hematology and Stem Cells. All rights reserved.
引用
收藏
页码:761 / 768
页数:8
相关论文
共 103 条
[1]   Hematopoietic support and cytokine expression of murine-stable hepatocyte cell lines (MMH) [J].
Aiuti, A ;
Cicchini, C ;
Bernardini, S ;
Fedele, G ;
Amicone, L ;
Fantoni, A ;
Tripodi, M .
HEPATOLOGY, 1998, 28 (06) :1645-1654
[2]   Long-term hematopoietic stem cells require stromal cell-derived factor-1 for colonizing bone marrow during ontogeny [J].
Ara, T ;
Tokoyoda, K ;
Sugiyama, T ;
Egawa, T ;
Kawabata, K ;
Nagasawa, T .
IMMUNITY, 2003, 19 (02) :257-267
[3]   Role of N-cadherin in the regulation of hematopoietic stem cells in the bone marrow niche [J].
Arai, Fumio ;
Hosokawa, Kentaro ;
Toyama, Hirofumi ;
Matsumoto, Yoshiko ;
Suda, Toshio .
HEMATOPOIETIC STEM CELLS VIII, 2012, 1266 :72-77
[4]   CD44 and hyaluronic acid cooperate with SDF-1 in the trafficking of human CD34+ stem/progenitor cells to bone marrow [J].
Avigdor, A ;
Goichberg, P ;
Shivtiel, S ;
Dar, A ;
Peled, A ;
Samira, S ;
Kollet, O ;
Hershkoviz, R ;
Alon, R ;
Hardan, I ;
Ben-Hur, H ;
Naor, D ;
Nagler, A ;
Lapidot, T .
BLOOD, 2004, 103 (08) :2981-2989
[5]   Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling [J].
Bafico, A ;
Gazit, A ;
Pramila, T ;
Finch, PW ;
Yaniv, A ;
Aaronson, SA .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (23) :16180-16187
[6]   Fetal spleen stroma drives macrophage commitment [J].
Bertrand, Julien Y. ;
Desanti, Guillaume E. ;
Lo-Man, Richard ;
Leclerc, Claude ;
Cumano, Ana ;
Golub, Rachel .
DEVELOPMENT, 2006, 133 (18) :3619-3628
[7]   Identification of a new intrinsically timed developmental checkpoint that reprograms key hematopoietic stem cell properties [J].
Bowie, Michelle B. ;
Kent, David G. ;
Dykstra, Brad ;
McKnight, Kristen D. ;
McCaffrey, Lindsay ;
Hoodless, Pamela A. ;
Eaves, Connie J. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (14) :5878-5882
[8]   Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defect [J].
Bowie, Michelle B. ;
McKnight, Kristen D. ;
Kent, David G. ;
McCaffrey, Lindsay ;
Hoodless, Pamela A. ;
Eaves, Connie J. .
JOURNAL OF CLINICAL INVESTIGATION, 2006, 116 (10) :2808-2816
[9]   Osteoblastic cells regulate the haematopoietic stem cell niche [J].
Calvi, LM ;
Adams, GB ;
Weibrecht, KW ;
Weber, JM ;
Olson, DP ;
Knight, MC ;
Martin, RP ;
Schipani, E ;
Divieti, P ;
Bringhurst, FR ;
Milner, LA ;
Kronenberg, HM ;
Scadden, DT .
NATURE, 2003, 425 (6960) :841-846
[10]   Functional characterization of WNT7A signaling in PC12 cells -: Interaction with a FZD5•LRP6 receptor complex and modulation by dickkopf proteins [J].
Caricasole, A ;
Ferraro, T ;
Iacovelli, L ;
Barletta, E ;
Caruso, A ;
Melchiorri, D ;
Terstappen, GC ;
Nicoletti, F .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (39) :37024-37031