Profile of Pregnant Women with Gestational Diabetes Mellitus at Increased Risk for Large for Gestational Age Newborns

被引:5
作者
Rodrigues Tavares, Maria da Gloria [1 ]
Lopes, Erika Sales [1 ]
Pereira Araujo Barros, Rosy Anne de Jesus [2 ]
de Sousa Azulay, Rossana Santiago [1 ]
Faria, Manuel dos Santos [1 ]
机构
[1] Univ Fed Maranhao, Endocrinol Unit, Univ Hosp, Sao Luis, MA, Brazil
[2] Univ Fed Maranhao, Dept Obstet & Gynecol, Sao Luis, MA, Brazil
来源
REVISTA BRASILEIRA DE GINECOLOGIA E OBSTETRICIA | 2019年 / 41卷 / 05期
关键词
gestational diabetes mellitus; oral glucose tolerance test; large for gestational age; WEIGHT-GAIN; GLUCOSE-TOLERANCE; HYPERGLYCEMIA; OBESITY; RECOMMENDATIONS; CLASSIFICATION; MACROSOMIA; METABOLISM;
D O I
10.1055/s-0039-1687860
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective Gestational diabetes mellitus (GDM) is associated with a higher risk of perinatal morbidity and mortality, and its main complication is the occurrence of large for gestational age (LGA) newborns. The present study aims to characterize pregnant women with GDM and to identify factors associated with the occurrence of LGA newborns in this population. Methods A cross-sectional study was performed based on medical records of women whose prenatal care and delivery were performed at the Maternal and Child Unit of the Hospital Universitario of the Universidade Federal do Maranhao, state of Maranhao, Brazil. A total of 116 pregnant women diagnosed with GDM were included according to the criteria of the International Association of Diabetes and Pregnancy Study Groups (IADPSG). Results The variables associated with LGA newborns after multivariate analysis were: obesity prior to pregnancy (OR = 11.6; 95% CI: 1.40-95.9), previous macrosomia (OR = 34.7; 95% CI: 4.08-295.3), high blood glucose levels in the 3rd trimester (OR = 2,67; 95% CI: 1.01-7.12) and combined change in the oral glucose tolerance test (OGTT) (fasting + postdextrose) (OR = 3.53; 95% CI: 1.25-14.2) = 1.17-10.6). Otherwise, insufficient weight gain during pregnancy reduced the risk for LGA newborns (OR = 0.04; 95% CI: 0.01-0.32). Conclusion Obesity prior to pregnancy, previous macrosomia, high blood glucose levels in the 3rd trimester, and combined change in the OGTT were independent predictive factors for LGA newborns in pregnant women with GDM.
引用
收藏
页码:298 / 305
页数:8
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