Colorectal Cancer and Dysplasia in Inflammatory Bowel Disease: A Review of Disease Epidemiology, Pathophysiology, and Management

被引：131

作者：

Dulai, Parambir S. ^{[1
]}

Sandborn, William J. ^{[1
]}

Gupta, Samir ^{[1
,2
,3
]}

机构：

[1] Univ Calif San Diego, Div Gastroenterol, La Jolla, CA 92093 USA

[2] Vet Affairs San Diego Healthcare Syst, San Diego, CA USA

[3] Univ Calif San Diego, Moores Canc Ctr, La Jolla, CA 92093 USA

来源：

CANCER PREVENTION RESEARCH | 2016年 / 9卷 / 12期

关键词：

PRIMARY SCLEROSING CHOLANGITIS; NF-KAPPA-B; EVIDENCE-BASED CONSENSUS; POPULATION-BASED COHORT; CROHNS COLITIS PATIENTS; BLOCKING TNF-ALPHA; LONG-TERM SAFETY; ULCERATIVE-COLITIS; RISK-FACTOR; COLONOSCOPIC SURVEILLANCE;

D O I：

10.1158/1940-6207.CAPR-16-0124

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Crohn disease and ulcerative colitis are chronic inflammatory bowel diseases (IBD) characterized by recurrent episodes of mucosal inflammation. This chronic mucosal inflammation has several potential consequences, one of which is the occurrence of colitis-associated colorectal cancer. Over the past understanding of the epidemiology, pathophysiology, and overall approach to diagnosing and managing colitis-associated colorectal cancer has grown considerably. In the current review article, we outline these advancements and highlight areas in need of further research.

引用

页码：887 / 894

页数：8

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