Aspirin and NSAIDs for the Prevention of Colorectal Cancer

被引：0
|
作者：
Baron, John A. [1 ]
机构：
[1] Evergreen Ctr, Lebanon, NH 03756 USA
来源：
CANCER PREVENTION II | 2009年 / 181卷
关键词：
NONSTEROIDAL ANTIINFLAMMATORY DRUGS; LOW-DOSE ASPIRIN; RANDOMIZED-TRIAL; CYCLOOXYGENASE-2; INHIBITOR; RISK; CHEMOPREVENTION; CELECOXIB; ADENOMAS; RECURRENCE; ROFECOXIB;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
With few exceptions, epidemiological studies have found that individuals who take nonsteroidal antiinflammatory drugs (NSAIDs) have a reduced risk of colorectal adenomas and carcinoma. Similarly, randomized studies in patients with familial adenomatous polyposis have uniformly found that NSAIDs can lead to polyp regression and prevention of new polyps, and trials in patients with sporadic adenomas document that aspirin reduces the risk of adenoma recurrence. Together these data provide convincing evidence for the chemopreventive efficacy of NSAIDs in the large bowel.
引用
收藏
页码：223 / 229
页数：7
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