Highly Efficient Assembly of 3-Hydroxy Oxindole Scaffold via a Catalytic Decarboxylative [1,2]-Addition Strategy

被引：41

作者：

Ren, Qiao ^{[2
]}

Huang, Jiayao ^{[2
]}

Wang, Lei ^{[2
]}

Li, Wenjun ^{[2
]}

Liu, Hui ^{[1
]}

Jiang, Xuefeng ^{[1
]}

Wang, Jian ^{[2
]}

机构：

[1] E China Normal Univ, Shanghai Key Lab Green Chem & Chem Proc, Shanghai 200062, Peoples R China

[2] Natl Univ Singapore, Dept Chem, Singapore 117543, Singapore

来源：

ACS CATALYSIS | 2012年 / 2卷 / 12期

关键词：

decarboxylation; 1,2-addition; organocatalysis; oxindole; ORGANOCATALYTIC ASYMMETRIC-SYNTHESIS; ENANTIOSELECTIVE SYNTHESIS; HALF-THIOESTERS; HYDROXYLATION; INHIBITORS; REAGENTS; BEARING; ACETONE; ESTERS;

D O I：

10.1021/cs300628w

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The 3-hydroxy-2-oxindole scaffold is being continuously discovered to be at the core of a diverse set of natural products. Herein, we document a highly efficient catalytic decarboxylative [1,2]-addition strategy to quickly assemble this scaffold, using a catalytic amount of weak base.

引用

页码：2622 / 2625

页数：4

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