Management of patients with cardiac stents undergoing noncardiac surgery

被引:16
作者
Schouten, Olaf [1 ]
Bax, Jeroen J. [3 ]
Poldermans, Don [2 ]
机构
[1] Erasmus MC, Dept Vasc Surg, Rotterdam, Netherlands
[2] Erasmus MC, Dept Anesthesiol, Rotterdam, Netherlands
[3] Leiden Univ, Med Ctr, Dept Cardiol, Leiden, Netherlands
关键词
antiplatelet therapy; bleeding; coronary stents; noncardiac surgery; stent thrombosis;
D O I
10.1097/ACO.0b013e328105dac5
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Purpose of review Coronary stenting is performed in over 4 million patients annually. Approximately 5% of these patients undergo a noncardiac surgical procedure within 1 year after stenting. Surgery might induce hypercoagulability. This causes increased concern about the effects of previous coronary stenting on postoperative cardiac outcome, particularly instent thrombosis. On the other hand, patients with multiple cardiac risk factors are at high risk for postoperative adverse cardiac events and might even benefit from preoperative prophylactic coronary revascularization. Recent findings Early noncardiac surgery after coronary stent placement is associated with an increased risk of major adverse cardiac events. The majority of these events are attributable to instent thrombosis. Antiplatelet therapy interruption in the perioperative period seems to be associated with an increase in adverse cardiac events, particularly in patients who undergo noncardiac surgery early after coronary stenting. Furthermore, prophylactic coronary revascularization for high cardiac risk patients is not associated with an improved outcome. Summary Early noncardiac surgery after coronary stenting increases the risk of postoperative cardiac events. Interruption of antiplatelet therapy seems to play an important role in this increased event rate. Prophylactic coronary revascularization in cardiac stable, but high-risk patients does not seem to improve outcome.
引用
收藏
页码:274 / 278
页数:5
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