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Recent Advances in Perioperative Anesthetic Management Update in the Perioperative Support of Patients with Septic Shock and the Effect on Outcomes
被引:3
|作者:
Douglas, Aaron
Wurm, Ellen
Pickett, Patrick
Hata, J. Steven
[1
]
机构:
[1] Cleveland Clin, Ctr Crit Care, Inst Anesthesiol, Dept Outcomes Res, Cleveland, OH 44106 USA
关键词:
Severe sepsis;
septic shock;
outcomes research;
CRITICALLY-ILL PATIENTS;
INTENSIVE-CARE-UNIT;
MECHANICALLY VENTILATED PATIENTS;
CLINICAL-PRACTICE GUIDELINES;
SURVIVING SEPSIS CAMPAIGN;
FC-MEDIATED PHAGOCYTOSIS;
CENTRAL VENOUS-PRESSURE;
FLUID RESPONSIVENESS;
INSULIN THERAPY;
ANTIBIOTIC-THERAPY;
D O I:
10.2174/138161212803832263
中图分类号:
R9 [药学];
学科分类号:
1007 ;
摘要:
Septic shock during the perioperative period imparts significant challenges for anesthetic management. There is increasing support for standardization of care using evidence-based, international consensus guidelines, such as the Surviving Sepsis Campaign. This review will highlight practices in the supportive management relevant to the perioperative care of patients with severe sepsis or septic shock and their effect on clinical outcomes. It will address the epidemiological data of sepsis, the diagnostic criteria, and the role of routine, goal-directed hemodynamic resuscitation. Furthermore, it will review other options for support, including antibiotics, intensive insulin therapy, and intensive care sedation in this high risk patient population.
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页码:6298 / 6307
页数:10
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