Multiple Relapses of Visceral Leishmaniasis in HIV Co-Infected Patients: A Case Series from Ethiopia

被引：18

作者：

Mohammed, Rezika ^{[1
,2
]}

Fikre, Helina ^{[1
]}

Schuster, Angela ^{[3
]}

Mekonnen, Tigist ^{[1
]}

van Griensven, Johan ^{[3
]}

Diro, Ermias ^{[2
]}

机构：

[1] Univ Gondar, Leishmaniasis Res & Treatment Ctr, Gondar, Ethiopia

[2] Univ Gondar, Dept Internal Med, POB 196, Gondar, Ethiopia

[3] Inst Trop Med, Dept Clin Sci, Antwerp, Belgium

来源：

CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL | 2020年 / 92卷

关键词：

VIRUS-COINFECTED PATIENTS; AMPHOTERICIN-B; SUSCEPTIBILITY; INFANTUM; RISK; AIDS;

D O I：

10.1016/j.curtheres.2020.100583

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Background: Human visceral leishmaniasis (VL) is a life-threatening protozoan disease caused by para-sites belonging to the Leishmania donovani complex. Ethiopia has the highest VL-HIV co-infection rate in the world, with several of these patients presenting with repeated episodes of VL disease (ie, relapse). However, we lack data on how HIV patients with multiple VL relapse present clinically, and whether they continue to respond to currently available medicines. p p p p p p ( http://creativecommons.org/licenses/by-nc-nd/4.0/ )

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