Lignans and coumarins metabolites from Melicope hayesii

被引:55
作者
Latip, J
Hartley, TG
Waterman, PG [1 ]
机构
[1] Univ Strathclyde, Dept Pharmaceut Sci, Phytochem Res Labs, Glasgow G1 1XW, Lanark, Scotland
[2] CSIRO, Div Plant Ind, Australian Natl Herbarium, Canberra, ACT 2601, Australia
关键词
Melicope hayesii; Rutaceae; lignan; (+)-2-(3,4-dimethoxyphenyl)-6-(3,4-dihydroxyphenyl)-3,7-dioxabicyclo[3,3,0]octane, coumarin; (+)-7-(3-methyl-4-carboxybutanoxy)umbelliferone methyl ester;
D O I
10.1016/S0031-9422(98)00720-1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Two novel compounds, the lignan, (+)-2-(3,4-dimethoxyphenyl)-6-(3,4-dihydroxyphenyl)-3,7-dioxabicyclo [3,3,0]octane, and the coumarin, (+)-7-(3-methyl-4-carboxybutanoxy)umbelliferone methyl ester, have been isolated from the aerial parts of Melicope hayesii. The known compounds, eudesmin, kobusin, N-p-coumaroyltyramine, N-methyl-2-pyrrolidinone, umbelliferone and 7-(3-methylbut-2-enoxy)umbelliferone were also obtained. Their structures were determined by extensive NMR studies. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:107 / 110
页数:4
相关论文
共 15 条
[1]  
Atta-ur-Rahman, 1992, PHYTOCHEMISTRY, V31, P2869
[2]  
BUT KM, 1987, BIOCH SYST ECOL, V15, P587
[3]   CHEMICAL CONSTITUENTS OF EVODIA MICROCOCCA [J].
CAMERON, DW ;
SUTHERLAND, MD .
AUSTRALIAN JOURNAL OF CHEMISTRY, 1961, 14 (01) :135-+
[4]   C-13 MAGNETIC-RESONANCE SPECTROSCOPY OF COUMARINS - C-13-PROTON LONG-RANGE COUPLINGS [J].
CHANG, CJ ;
FLOSS, HG ;
STECK, W .
JOURNAL OF ORGANIC CHEMISTRY, 1977, 42 (08) :1337-1340
[5]  
FIESER LF, 1967, REAGENTS ORG SYNTH, V1, P696
[6]   NEW COUMARINS FROM COLEONEMA-ALBUM [J].
GRAY, AI .
PHYTOCHEMISTRY, 1981, 20 (07) :1711-1713
[7]  
HARTLEY T G, 1990, Telopea, V4, P33
[8]   HYDROPEROXYSESQUITERPENE AND LIGNAN CONSTITUENTS OF MAGNOLIA-KOBUS [J].
IIDA, T ;
NAKANO, M ;
ITO, K .
PHYTOCHEMISTRY, 1982, 21 (03) :673-675
[9]   COUMARINS FROM RESIN OF EUODIA-VITIFLORA [J].
LASSAK, EV ;
SOUTHWELL, IA .
AUSTRALIAN JOURNAL OF CHEMISTRY, 1972, 25 (11) :2491-+
[10]  
Mabry T.J., 2012, SYSTEMATIC IDENTIFIC