Chitosan/poly (vinyl pyrollidone) coatings improve the antibacterial properties of poly(ethylene terephthalate)

被引：72
作者：
Wang, Bai-liang [1 ]
Wang, Jin-lei [1 ]
Li, Dan-dan [1 ]
Ren, Ke-feng [1 ]
Ji, Jian [1 ]
机构：
[1] Zhejiang Univ, Dept Polymer Sci & Engn, MOE Key Lab Macromol Synth & Functionalizat, Hangzhou 310027, Peoples R China
来源：
APPLIED SURFACE SCIENCE | 2012年 / 258卷 / 20期
关键词：
Chitosan; PVP; Antibacterial; Antiadhesion; Coating; SURFACE MODIFICATION; BACTERIAL ADHESION; MULTILAYER FILMS; POLYESTER; BIOFILMS; NANOPARTICLES; INFECTIONS; MEMBRANES; BLEND; ACID;
D O I：
10.1016/j.apsusc.2012.03.181
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
Chitosan/poly (vinyl pyrollidone) (CHI/PVP) coatings were prepared to improve the antibacterial properties of poly (ethylene terephthalate) (PET) by a simple dip-coating method. The binding capability of CHI/PVP coatings was enhanced by successively pretreatment of PET by polyetherimide and polyacrylic acid and crosslinking. Measurements of water contact angle and atomic force microscope revealed that the coatings created a highly hydrophilic surface with low roughness. Adherences of Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) on PET with CHI/PVP coating were significantly reduced. Bactericidal activity of CHI/PVP coatings was good against E. coli and S. aureus and the adding of PVP obviously increased its antiadhesion property. In vitro cytotoxicity tests, cell morphology and activity evaluation of human umbilical vein endothelial cells showed that CHI/PVP coatings had good biocompatibility. (C) 2012 Elsevier B.V. All rights reserved.
引用
收藏
页码：7801 / 7808
页数：8
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