Staging investigations in patients with breast cancer -: The role of bone scans and liver imaging

被引:47
作者
Samant, R
Ganguly, P
机构
[1] Univ British Columbia, Fac Med, Dept Surg, Vancouver, BC, Canada
[2] Mem Univ Newfoundland, Fac Med, Dept Med, St Johns, NF, Canada
关键词
D O I
10.1001/archsurg.134.5.551
中图分类号
R61 [外科手术学];
学科分类号
摘要
Hypothesis: Metastatic workup for patients newly diagnosed as having breast cancer is variable, especially for early disease (T1-2 N0-1). Routine bone scans and liver imaging are often performed without any evidence to support their usefulness. Design: A retrospective review of patients with breast cancer referred to our center during a 2-year period was performed to determine the value of staging investigations in detecting metastases. Results: Of the total 250 patients referred to our center after initial diagnosis, 25 (10.0%) were diagnosed as having metastases, 23 of whom had either clinical symptoms or signs suggestive of metastatic disease or abnormalities on routine blood work or chest x-ray examinations. Only 2 patients with metastatic disease were diagnosed solely an bone scan results; none were diagnosed solely on liver imaging (either with an ultrasound or radionuclide isotope liver scan). Overall, 3% (5/161) of patients with pathologic T1-2 N0-1 disease had metastases diagnosed compared with 30% (18/61) of patients with pathologic stage T3-4 or N2 disease. Conclusions: Our results confirm the low yield of routine bone scans and liver imaging among patients with asymptomatic, pathologically confirmed, early stage (T1-2 N0-1) breast cancer. Therefore, we do not recommend these tests for such patients, although intensive investigations are appropriate for more advanced (stage T3-4 or NZ) tumors.
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页码:551 / 553
页数:3
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